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    SYNE2 spectrin repeat containing nuclear envelope protein 2 [ Gallus gallus (chicken) ]

    Gene ID: 423509, updated on 17-Aug-2024

    Summary

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    Symbol
    SYNE2provided by CGNC
    Full Name
    spectrin repeat containing nuclear envelope protein 2provided by CGNC
    Primary source
    CGNC:8956
    See related
    Ensembl:ENSGALG00010017621
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SYNE2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    120
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (52557750..52731667, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (52536002..52711161, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418020 Neighboring gene A-kinase anchoring protein 5 Neighboring gene methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Neighboring gene estrogen receptor 2 Neighboring gene uncharacterized LOC121110835 Neighboring gene transfer RNA leucine (anticodon CAG) Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC107053571 Neighboring gene uncharacterized LOC121110834 Neighboring gene sphingosine-1-phosphate phosphatase 1 Neighboring gene WD repeat domain 89

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nesprin-2
    Names
    spectrin repeat containing, nuclear envelope 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      52557750..52731667 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701588.2 → XP_040557522.1  nesprin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3397 → 3976
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2915 → 3754
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6216 → 6426
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5387 → 6104
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2318
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4828 → 4980
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_015287885.4 → XP_015143371.2  nesprin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Related
      ENSGALP00010025099.1, ENSGALT00010042609.1

    3. XM_015287883.4 → XP_015143369.2  nesprin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3406 → 3985
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2924 → 3763
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6225 → 6435
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5396 → 6113
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4837 → 4989
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_015287888.4 → XP_015143374.2  nesprin-2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG1196
      Location:2781 → 3547
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      PRK03918
      Location:3335 → 3939
      PRK03918; DNA double-strand break repair ATPase Rad50
      cd00176
      Location:6154 → 6364
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5325 → 6042
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2394
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4766 → 4918
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_015287886.4 → XP_015143372.2  nesprin-2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YVK2, A0A8V0Z202
      Related
      ENSGALP00010025106.1, ENSGALT00010042616.1
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5397 → 6114
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_015287884.4 → XP_015143370.2  nesprin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5397 → 6114
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    7. XM_015287882.4 → XP_015143368.2  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVI8, A0A8V0YVK2
      Related
      ENSGALP00010025084.1, ENSGALT00010042594.1
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5397 → 6114
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    8. XM_040701587.2 → XP_040557521.1  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVI8, A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5397 → 6114
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    9. XM_040701586.2 → XP_040557520.1  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVI8, A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:5397 → 6114
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      52536002..52711161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040672010.2 → XP_040527944.1  nesprin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3397 → 3976
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2915 → 3754
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6216 → 6426
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2318
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4828 → 4980
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_040672009.2 → XP_040527943.1  nesprin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3398 → 3977
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2916 → 3755
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6217 → 6427
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2318
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4829 → 4981
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_040672007.2 → XP_040527941.1  nesprin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3406 → 3985
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2924 → 3763
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6225 → 6435
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4837 → 4989
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_040672012.2 → XP_040527946.1  nesprin-2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG1196
      Location:2781 → 3547
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      PRK03918
      Location:3335 → 3939
      PRK03918; DNA double-strand break repair ATPase Rad50
      cd00176
      Location:6154 → 6364
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4766 → 4918
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_040672011.2 → XP_040527945.1  nesprin-2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_040672008.2 → XP_040527942.1  nesprin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    7. XM_040672004.2 → XP_040527938.1  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    8. XM_040672006.2 → XP_040527940.1  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    9. XM_040672005.2 → XP_040527939.1  nesprin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YVK2
      Conserved Domains (8) summary
      COG0419
      Location:3407 → 3986
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:2925 → 3764
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5069
      Location:25 → 279
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:6226 → 6436
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      TIGR02168
      Location:771 → 1592
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15921
      Location:1630 → 2327
      CCDC158; Coiled-coil domain-containing protein 158
      cl02488
      Location:1386 → 1593
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl38936
      Location:4838 → 4990
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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