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    PARP3 poly(ADP-ribose) polymerase family member 3 [ Gallus gallus (chicken) ]

    Gene ID: 771158, updated on 3-Dec-2024

    Summary

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    Symbol
    PARP3provided by CGNC
    Full Name
    poly(ADP-ribose) polymerase family member 3provided by CGNC
    Primary source
    CGNC:3337
    See related
    Ensembl:ENSGALG00010027567
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PARP3 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (3327404..3331135, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (3376724..3380535, complement)

    Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 2-like Neighboring gene alpha/beta hydrolase domain-containing protein 14B-like Neighboring gene poly(rC) binding protein 4 Neighboring gene G protein-coupled receptor 62 Neighboring gene RNA binding motif protein 10 Neighboring gene semaphorin 3F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Grundy GJ, et al. Nat Commun, 2016 Aug 17. PMID 27530147, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data identify PARP3 as a molecular sensor of nicked nucleosomes.
      Title: PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly [ADP-ribose] polymerase 3; protein mono-ADP-ribosyltransferase PARP3
    XP_015148336.2
    XP_015148337.2
    XP_015148338.2
    XP_040537823.1
    XP_040537824.1
    XP_040537825.1
    XP_046756083.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      3327404..3331135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015292852.4 → XP_015148338.2  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      UniProtKB/TrEMBL
      A0A8V1ACA7
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

    2. XM_015292851.4 → XP_015148337.2  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      UniProtKB/TrEMBL
      A0A8V1ACA7
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

    3. XM_015292850.4 → XP_015148336.2  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      UniProtKB/TrEMBL
      A0A8V1ACA7
      Related
      ENSGALP00010040866.1, ENSGALT00010066775.1
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

    4. XM_046900127.1 → XP_046756083.1  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      UniProtKB/TrEMBL
      A0A8V1ACA7

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      3376724..3380535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040681890.2 → XP_040537824.1  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

    2. XM_040681891.2 → XP_040537825.1  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

    3. XM_040681889.2 → XP_040537823.1  protein mono-ADP-ribosyltransferase PARP3

      UniProtKB/Swiss-Prot
      A0A3Q2UAE2, E1BSI0
      Conserved Domains (2) summary
      cd08002
      Location:60 → 158
      WGR_PARP3_like; WGR domain of poly(ADP-ribose) polymerase 3 and similar proteins
      cd01437
      Location:183 → 525
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...
    Nucleotide Protein Strain
    Heading Accession and Version

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