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    FRMD4B FERM domain containing 4B [ Gallus gallus (chicken) ]

    Gene ID: 426071, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FRMD4Bprovided by CGNC
    Official Full Name
    FERM domain containing 4Bprovided by CGNC
    Primary source
    CGNC:52665
    See related
    Ensembl:ENSGALG00010020127
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See FRMD4B in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (15528967..15629445, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (15562606..15663060, complement)

    Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 5 Neighboring gene leiomodin 3 Neighboring gene uncharacterized LOC121106660 Neighboring gene melanocyte inducing transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in establishment of epithelial cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FERM domain-containing protein 4B
    Names
    GRP1-binding protein GRSP1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      15528967..15629445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040646786.2 → XP_040502720.1  FERM domain-containing protein 4B isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z672
      Related
      ENSGALP00010028743.1, ENSGALT00010048652.1
      Conserved Domains (3) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    2. XM_423748.8 → XP_423748.2  FERM domain-containing protein 4B isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z672, A0A8V0ZCX4
      Related
      ENSGALP00010028736.1, ENSGALT00010048645.1
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    3. XM_004944685.5 → XP_004944742.1  FERM domain-containing protein 4B isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z672
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    4. XM_040646788.2 → XP_040502722.1  FERM domain-containing protein 4B isoform X10

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Related
      ENSGALP00010028723.1, ENSGALT00010048632.1
      Conserved Domains (2) summary
      smart00295
      Location:85 → 134
      B41; Band 4.1 homologues
      cd13191
      Location:130 → 240
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

    5. XM_015293247.4 → XP_015148733.1  FERM domain-containing protein 4B isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Related
      ENSGALP00010028718.1, ENSGALT00010048627.1
      Conserved Domains (4) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:341 → 474
      DUF3338; Domain of unknown function (DUF3338)

    6. XM_015293242.4 → XP_015148728.1  FERM domain-containing protein 4B isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (4) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:341 → 474
      DUF3338; Domain of unknown function (DUF3338)

    7. XM_015293240.4 → XP_015148726.1  FERM domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    8. XM_015293239.4 → XP_015148725.1  FERM domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (3) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    9. XM_040646785.2 → XP_040502719.1  FERM domain-containing protein 4B isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (3) summary
      smart00295
      Location:54 → 254
      B41; Band 4.1 homologues
      cd13191
      Location:250 → 360
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:51 → 139
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    10. XM_040646787.1 → XP_040502721.1  FERM domain-containing protein 4B isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Conserved Domains (3) summary
      cd13191
      Location:89 → 199
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam00373
      Location:27 → 93
      FERM_M; FERM central domain
      pfam11819
      Location:228 → 361
      DUF3338; Domain of unknown function (DUF3338)

    11. XM_015293245.4 → XP_015148731.2  FERM domain-containing protein 4B isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Conserved Domains (2) summary
      smart00295
      Location:85 → 134
      B41; Band 4.1 homologues
      cd13191
      Location:130 → 240
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      15562606..15663060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040682472.2 → XP_040538406.1  FERM domain-containing protein 4B isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z672
      Conserved Domains (3) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    2. XM_040682469.2 → XP_040538403.1  FERM domain-containing protein 4B isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z672, A0A8V0ZCX4
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    3. XM_040682468.2 → XP_040538402.1  FERM domain-containing protein 4B isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z672
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    4. XM_040682475.2 → XP_040538409.1  FERM domain-containing protein 4B isoform X10

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Conserved Domains (2) summary
      smart00295
      Location:85 → 134
      B41; Band 4.1 homologues
      cd13191
      Location:130 → 240
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

    5. XM_040682470.2 → XP_040538404.1  FERM domain-containing protein 4B isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (4) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:341 → 474
      DUF3338; Domain of unknown function (DUF3338)

    6. XM_040682471.2 → XP_040538405.1  FERM domain-containing protein 4B isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (4) summary
      smart00295
      Location:6 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:341 → 474
      DUF3338; Domain of unknown function (DUF3338)

    7. XM_040682466.2 → XP_040538400.1  FERM domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (4) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:395 → 528
      DUF3338; Domain of unknown function (DUF3338)

    8. XM_040682465.2 → XP_040538399.1  FERM domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (3) summary
      smart00295
      Location:60 → 260
      B41; Band 4.1 homologues
      cd13191
      Location:256 → 366
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:57 → 145
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    9. XM_040682467.2 → XP_040538401.1  FERM domain-containing protein 4B isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZJE2
      Conserved Domains (3) summary
      smart00295
      Location:54 → 254
      B41; Band 4.1 homologues
      cd13191
      Location:250 → 360
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:51 → 139
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

    10. XM_040682474.1 → XP_040538408.1  FERM domain-containing protein 4B isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Conserved Domains (3) summary
      cd13191
      Location:89 → 199
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam00373
      Location:27 → 93
      FERM_M; FERM central domain
      pfam11819
      Location:228 → 361
      DUF3338; Domain of unknown function (DUF3338)

    11. XM_040682473.2 → XP_040538407.1  FERM domain-containing protein 4B isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZJE7
      Conserved Domains (2) summary
      smart00295
      Location:85 → 134
      B41; Band 4.1 homologues
      cd13191
      Location:130 → 240
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    Nucleotide Protein Strain
    Heading Accession and Version

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