LAMA5 laminin subunit alpha 5 [Gallus gallus (chicken)] - Gene

Summary

Symbol: LAMA5provided by CGNC
Full Name: laminin subunit alpha 5provided by CGNC
Primary source: CGNC:3962
See related: Ensembl:ENSGALG00010022979
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 81

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	20	NC_052551.1 (8173533..8253131, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	20	NC_052592.1 (7956676..8036244, complement)

Chromosome 20 - NC_052551.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Laminin alpha5, a gene up-regulated during neural crest induction, is localized in regions of newly formed cranial and trunk neural folds and adjacent neural crest migratory pathways in a manner largely conserved between chick and mouse.
Title: Abnormalities in neural crest cell migration in laminin alpha5 mutant mice.

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of embryonic development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in basement membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: laminin subunit alpha-5

Names: laminin, alpha 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

8173533..8253131 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040650754.2 → XP_040506688.1 laminin subunit alpha-5 isoform X4

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2016 → 2060

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1634 → 1761

LamB; Laminin B domain

smart00282
Location:2726 → 2853

LamG; Laminin G domain

COG1196
Location:2334 → 2685

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1525 → 1575

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3287 → 3440

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2136 → 2394

Laminin_I; Laminin Domain I

pfam06009
Location:2577 → 2705

Laminin_II; Laminin Domain II
XM_015296661.4 → XP_015152147.2 laminin subunit alpha-5 isoform X3

UniProtKB/TrEMBL

A0A8V0ZKI3

Related

ENSGALP00010033878.1, ENSGALT00010055980.1

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2060 → 2104

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1678 → 1805

LamB; Laminin B domain

smart00282
Location:2770 → 2897

LamG; Laminin G domain

COG1196
Location:2378 → 2729

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1569 → 1619

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3331 → 3484

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2180 → 2438

Laminin_I; Laminin Domain I

pfam06009
Location:2621 → 2749

Laminin_II; Laminin Domain II
XM_015296660.4 → XP_015152146.2 laminin subunit alpha-5 isoform X2

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2062 → 2106

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1680 → 1807

LamB; Laminin B domain

smart00282
Location:2772 → 2899

LamG; Laminin G domain

COG1196
Location:2380 → 2731

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1571 → 1621

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3333 → 3486

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2182 → 2440

Laminin_I; Laminin Domain I

pfam06009
Location:2623 → 2751

Laminin_II; Laminin Domain II
XM_015296659.4 → XP_015152145.2 laminin subunit alpha-5 isoform X1

UniProtKB/TrEMBL

A0A8V0ZTP1

Related

ENSGALP00010033866.1, ENSGALT00010055959.1

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2063 → 2107

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1681 → 1808

LamB; Laminin B domain

smart00282
Location:2773 → 2900

LamG; Laminin G domain

COG1196
Location:2381 → 2732

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1572 → 1622

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3334 → 3487

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2183 → 2441

Laminin_I; Laminin Domain I

pfam06009
Location:2624 → 2752

Laminin_II; Laminin Domain II

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

7956676..8036244 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040687806.2 → XP_040543740.1 laminin subunit alpha-5 isoform X4

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2016 → 2060

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1634 → 1761

LamB; Laminin B domain

smart00282
Location:2726 → 2853

LamG; Laminin G domain

COG1196
Location:2334 → 2685

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1525 → 1575

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3287 → 3440

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2136 → 2394

Laminin_I; Laminin Domain I

pfam06009
Location:2577 → 2705

Laminin_II; Laminin Domain II
XM_040687805.2 → XP_040543739.1 laminin subunit alpha-5 isoform X3

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2060 → 2104

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1678 → 1805

LamB; Laminin B domain

smart00282
Location:2770 → 2897

LamG; Laminin G domain

COG1196
Location:2378 → 2729

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1569 → 1619

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3331 → 3484

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2180 → 2438

Laminin_I; Laminin Domain I

pfam06009
Location:2621 → 2749

Laminin_II; Laminin Domain II
XM_040687804.2 → XP_040543738.1 laminin subunit alpha-5 isoform X2

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2062 → 2106

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1680 → 1807

LamB; Laminin B domain

smart00282
Location:2772 → 2899

LamG; Laminin G domain

COG1196
Location:2380 → 2731

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1571 → 1621

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3333 → 3486

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2182 → 2440

Laminin_I; Laminin Domain I

pfam06009
Location:2623 → 2751

Laminin_II; Laminin Domain II
XM_040687802.2 → XP_040543736.1 laminin subunit alpha-5 isoform X1

Conserved Domains (9) summary

smart00136
Location:40 → 295

LamNT; Laminin N-terminal domain (domain VI)

smart00180
Location:2063 → 2107

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00281
Location:1681 → 1808

LamB; Laminin B domain

smart00282
Location:2773 → 2900

LamG; Laminin G domain

COG1196
Location:2381 → 2732

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd00055
Location:1572 → 1622

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3334 → 3487

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2183 → 2441

Laminin_I; Laminin Domain I

pfam06009
Location:2624 → 2752

Laminin_II; Laminin Domain II