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    ADARB1 adenosine deaminase, RNA specific B1 [ Gallus gallus (chicken) ]

    Gene ID: 374087, updated on 3-Dec-2024

    Summary

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    Symbol
    ADARB1provided by CGNC
    Full Name
    adenosine deaminase, RNA specific B1provided by CGNC
    Primary source
    CGNC:49038
    See related
    Ensembl:ENSGALG00010013527
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    RED1
    Annotation information
    Annotation category: suggests misassembly
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See ADARB1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (7292023..7358070)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (7226579..7303458)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 2 Neighboring gene family with sequence similarity 207 member A Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene uncharacterized LOC101747789 Neighboring gene glutaminase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic comparison of the pre-mRNA adenosine deaminase ADAR2 genes and transcripts: conservation and diversity in editing site sequence and alternative splicing patterns. Slavov D, et al. Gene, 2002 Oct 16. PMID 12459255
    2. ESTs from brain and testis of White Leghorn and red junglefowl: annotation, bioinformatic classification of unknown transcripts and analysis of expression levels. Savolainen P, et al. Cytogenet Genome Res, 2005. PMID 16093725
    3. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables double-stranded RNA adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tRNA-specific adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenosine to inosine editing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    double-stranded RNA-specific editase 1
    Names
    RNA-specific adenosine deaminase B1
    adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)
    NP_001104544.1
    NP_001383358.1
    NP_989571.1
    XP_046776808.1
    XP_046776809.1
    XP_046776810.1
    XP_046776811.1
    XP_046776812.1
    XP_046776813.1
    XP_046776814.1
    XP_046776815.1
    XP_046776816.1
    XP_046776817.1
    XP_046776818.1
    XP_046776819.1
    XP_046776820.1
    XP_046776821.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111074.2 → NP_001104544.1  double-stranded RNA-specific editase 1

      See identical proteins and their annotated locations for NP_001104544.1

      Status: VALIDATED

      Source sequence(s)
      JAENSL010000118
      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5
      Related
      ENSGALP00010019293.1, ENSGALT00010032568.1
      Conserved Domains (3) summary
      cd19895
      Location:76 → 147
      DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      cd19898
      Location:233 → 302
      DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      pfam02137
      Location:371 → 691
      A_deamin; Adenosine-deaminase (editase) domain

    2. NM_001396429.1 → NP_001383358.1  double-stranded RNA-specific editase 1

      Status: VALIDATED

      Source sequence(s)
      JAENSL010000118
      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5
      Conserved Domains (3) summary
      cd19895
      Location:76 → 147
      DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      cd19898
      Location:233 → 302
      DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      pfam02137
      Location:371 → 691
      A_deamin; Adenosine-deaminase (editase) domain

    3. NM_204240.3 → NP_989571.1  double-stranded RNA-specific editase 1

      See identical proteins and their annotated locations for NP_989571.1

      Status: VALIDATED

      Source sequence(s)
      JAENSL010000118
      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5
      Related
      ENSGALP00010019289.1, ENSGALT00010032563.1
      Conserved Domains (3) summary
      cd19895
      Location:76 → 147
      DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      cd19898
      Location:233 → 302
      DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
      pfam02137
      Location:371 → 691
      A_deamin; Adenosine-deaminase (editase) domain

    RNA

    1. NR_004440.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAENSL010000118

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      7292023..7358070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      7226579..7303458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046920853.1 → XP_046776809.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    2. XM_046920858.1 → XP_046776814.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    3. XM_046920854.1 → XP_046776810.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    4. XM_046920855.1 → XP_046776811.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    5. XM_046920865.1 → XP_046776821.1  double-stranded RNA-specific editase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YSW9

    6. XM_046920862.1 → XP_046776818.1  double-stranded RNA-specific editase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YSW9, Q90VV7

    7. XM_046920863.1 → XP_046776819.1  double-stranded RNA-specific editase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YSW9, Q90VV7

    8. XM_046920852.1 → XP_046776808.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    9. XM_046920856.1 → XP_046776812.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    10. XM_046920857.1 → XP_046776813.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    11. XM_046920861.1 → XP_046776817.1  double-stranded RNA-specific editase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YSW9

    12. XM_046920860.1 → XP_046776816.1  double-stranded RNA-specific editase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YSW9

    13. XM_046920859.1 → XP_046776815.1  double-stranded RNA-specific editase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YSW9, F6UXQ7, Q90VZ5

    14. XM_046920864.1 → XP_046776820.1  double-stranded RNA-specific editase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YSW9, Q90VV7
    Nucleotide Protein Strain
    Heading Accession and Version

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