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    SIPA1L2 signal induced proliferation associated 1 like 2 [ Gallus gallus (chicken) ]

    Gene ID: 421523, updated on 17-Aug-2024

    Summary

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    Symbol
    SIPA1L2provided by CGNC
    Full Name
    signal induced proliferation associated 1 like 2provided by CGNC
    Primary source
    CGNC:8379
    See related
    Ensembl:ENSGALG00010008151
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SIPA1L2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (38690198..38954267)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (38593760..38857869)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene pecanex 2 Neighboring gene uncharacterized LOC121110438 Neighboring gene nucleoside-triphosphatase, cancer-related Neighboring gene uncharacterized LOC121110437 Neighboring gene microtubule associated protein 10 Neighboring gene uncharacterized LOC121113191 Neighboring gene uncharacterized LOC100857993 Neighboring gene disrupted in schizophrenia 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal-induced proliferation-associated 1-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      38690198..38954267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040698284.2 → XP_040554218.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    2. XM_046939496.1 → XP_046795452.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2

    3. XM_046939497.1 → XP_046795453.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2

    4. XM_040698288.2 → XP_040554222.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Related
      ENSGALP00010010990.1, ENSGALT00010019442.1
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    5. XM_040698286.2 → XP_040554220.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    6. XM_419564.8 → XP_419564.3  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    7. XM_040698289.2 → XP_040554223.1  signal-induced proliferation-associated 1-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5P6H3
      Related
      ENSGALP00010010992.1, ENSGALT00010019444.1
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 690
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    8. XM_040698290.2 → XP_040554224.1  signal-induced proliferation-associated 1-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XWC9
      Related
      ENSGALP00010010993.1, ENSGALT00010019445.1
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 690
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    9. XM_040698291.2 → XP_040554225.1  signal-induced proliferation-associated 1-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5PEA3
      Related
      ENSGALP00010010994.1, ENSGALT00010019446.1
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 696
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    10. XM_040698292.2 → XP_040554226.1  signal-induced proliferation-associated 1-like protein 2 isoform X5

      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 696
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    11. XM_040698285.2 → XP_040554219.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      38593760..38857869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040668543.2 → XP_040524477.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    2. XM_046914895.1 → XP_046770851.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2

    3. XM_046914894.1 → XP_046770850.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2

    4. XM_040668545.2 → XP_040524479.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    5. XM_040668546.2 → XP_040524480.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein

    6. XM_040668547.2 → XP_040524481.1  signal-induced proliferation-associated 1-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5P6H3
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 690
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    7. XM_040668548.2 → XP_040524482.1  signal-induced proliferation-associated 1-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XWC9
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 690
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    8. XM_040668549.2 → XP_040524483.1  signal-induced proliferation-associated 1-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5PEA3
      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 696
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    9. XM_040668550.2 → XP_040524484.1  signal-induced proliferation-associated 1-like protein 2 isoform X5

      Conserved Domains (2) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19006
      Location:610 → 696
      Cas10d_I-D; CRISPR/Cas system-associated protein Cas10d

    10. XM_040668544.2 → XP_040524478.1  signal-induced proliferation-associated 1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y4J2
      Conserved Domains (3) summary
      cd00992
      Location:942 → 1014
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:619 → 799
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1421 → 1660
      SPAR_C; C-terminal domain of SPAR protein
    Nucleotide Protein Strain
    Heading Accession and Version

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