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    LDB2 LIM domain binding 2 [ Gallus gallus (chicken) ]

    Gene ID: 395631, updated on 3-Dec-2024

    Summary

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    Symbol
    LDB2provided by CGNC
    Full Name
    LIM domain binding 2provided by CGNC
    Primary source
    CGNC:49412
    See related
    Ensembl:ENSGALG00010011096
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CLIM-1
    Orthologs
    human mouse all
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    Genomic context

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    See LDB2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (75557183..75914501)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (75534504..75891959)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene clarin 2 Neighboring gene quinoid dihydropteridine reductase Neighboring gene uncharacterized LOC112532307 Neighboring gene uncharacterized LOC124417920 Neighboring gene transmembrane anterior posterior transformation 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain. Tran YH, et al. J Biochem, 2006 Jul. PMID 16815859
    2. RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. Bach I, et al. Nat Genet, 1999 Aug. PMID 10431247
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables LIM domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LIM domain-binding protein 2
    Names
    LDB-2
    LIM domain binding protein CLIM-1
    LIM domain-binding factor CLIM1
    cLdb2
    carboxyl-terminal LIM domain-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204829.2 → NP_990160.2  LIM domain-binding protein 2

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000074
      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676
      Related
      ENSGALP00010015150.1, ENSGALT00010026583.1
      Conserved Domains (2) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein
      pfam17916
      Location:296 → 324
      LID; LIM interaction domain (LID)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      75557183..75914501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046939902.1 → XP_046795858.1  LIM domain-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YGL3

    2. XM_015285735.4 → XP_015141221.1  LIM domain-binding protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YGM7
      Related
      ENSGALP00010015152.1, ENSGALT00010026586.1
      Conserved Domains (1) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein

    3. XM_015285728.4 → XP_015141214.1  LIM domain-binding protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676
      Related
      ENSGALP00010015137.1, ENSGALT00010026566.1
      Conserved Domains (2) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein
      pfam17916
      Location:298 → 326
      LID; LIM interaction domain (LID)

    4. XM_025149511.3 → XP_025005279.1  LIM domain-binding protein 2 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y3G0, A0A8V0YGM7
      Related
      ENSGALP00010015141.1, ENSGALT00010026571.1
      Conserved Domains (1) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein

    5. XM_040698711.2 → XP_040554645.1  LIM domain-binding protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A8V0YGM7

    6. XM_015285730.4 → XP_015141216.1  LIM domain-binding protein 2 isoform X2

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676
      Conserved Domains (2) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein
      pfam17916
      Location:297 → 325
      LID; LIM interaction domain (LID)

    7. XM_046939903.1 → XP_046795859.1  LIM domain-binding protein 2 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YGM2

    8. XM_015285731.4 → XP_015141217.1  LIM domain-binding protein 2 isoform X3

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676
      Conserved Domains (2) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein
      pfam17916
      Location:295 → 323
      LID; LIM interaction domain (LID)

    9. XM_040698708.2 → XP_040554642.1  LIM domain-binding protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YGM2

    10. XM_040698709.2 → XP_040554643.1  LIM domain-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y867, A0A8V0YGM7
      Related
      ENSGALP00010015145.1, ENSGALT00010026575.1
      Conserved Domains (1) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein

    11. XM_015285734.4 → XP_015141220.1  LIM domain-binding protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YGM2
      Related
      ENSGALP00010015147.1, ENSGALT00010026580.1
      Conserved Domains (1) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein

    12. XM_040698710.2 → XP_040554644.1  LIM domain-binding protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YGM2
      Conserved Domains (1) summary
      pfam01803
      Location:31 → 232
      LIM_bind; LIM-domain binding protein

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      75534504..75891959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915501.1 → XP_046771457.1  LIM domain-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YGL3

    2. XM_046915506.1 → XP_046771462.1  LIM domain-binding protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YGM7

    3. XM_046915498.1 → XP_046771454.1  LIM domain-binding protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676

    4. XM_046915508.1 → XP_046771464.1  LIM domain-binding protein 2 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y3G0, A0A8V0YGM7

    5. XM_046915507.1 → XP_046771463.1  LIM domain-binding protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A8V0YGM7

    6. XM_046915499.1 → XP_046771455.1  LIM domain-binding protein 2 isoform X2

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676

    7. XM_046915509.1 → XP_046771465.1  LIM domain-binding protein 2 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YGM2

    8. XM_046915500.1 → XP_046771456.1  LIM domain-binding protein 2 isoform X3

      UniProtKB/Swiss-Prot
      Q1EQW9, Q9W676

    9. XM_046915502.1 → XP_046771458.1  LIM domain-binding protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YGM2

    10. XM_046915503.1 → XP_046771459.1  LIM domain-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y867, A0A8V0YGM7

    11. XM_046915505.1 → XP_046771461.1  LIM domain-binding protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YGM2

    12. XM_046915504.1 → XP_046771460.1  LIM domain-binding protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YGM2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W676.1 GenPept UniProtKB/Swiss-Prot:Q9W676

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