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    PRSS2 protease, serine 1 [ Gallus gallus (chicken) ]

    Gene ID: 396344, updated on 17-Aug-2024

    Summary

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    Symbol
    PRSS2provided by CGNC
    Full Name
    protease, serine 1provided by CGNC
    Primary source
    CGNC:49760
    See related
    Ensembl:ENSGALG00010023541
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See PRSS2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (78112098..78115437, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (78315822..78319160, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene T cell receptor beta variable 6-5 Neighboring gene trypsin II-P29 Neighboring gene T cell receptor beta variable 19-like Neighboring gene T-cell receptor beta-2 chain C region-like Neighboring gene protease, serine, 3 Neighboring gene T cell receptor alpha variable 20-like Neighboring gene kallikrein-related peptidase 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of the chicken trypsinogen gene family. Wang K, et al. Biochem J, 1995 Apr 15. PMID 7733885, Free PMC Article
    2. The molecular evolution of the vertebrate trypsinogens. Roach JC, et al. J Mol Evol, 1997 Dec. PMID 9419241
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trypsin II-P29
    Names
    protease, serine 2
    protease, serine, 2 (trypsin 2)
    trypsinogen
    NP_990715.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205384.2 → NP_990715.1  trypsin II-P29 precursor

      See identical proteins and their annotated locations for NP_990715.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000016
      UniProtKB/Swiss-Prot
      Q90629
      UniProtKB/TrEMBL
      A0A8V0ZN26
      Related
      ENSGALP00010034844.1, ENSGALT00010057322.1
      Conserved Domains (2) summary
      smart00020
      Location:25 → 241
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:26 → 244
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      78112098..78115437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      78315822..78319160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q90629.1 GenPept UniProtKB/Swiss-Prot:Q90629

    Gene LinkOut

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    Research Materials