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    CPA2 carboxypeptidase A2 [ Gallus gallus (chicken) ]

    Gene ID: 416682, updated on 17-Aug-2024

    Summary

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    Symbol
    CPA2provided by CGNC
    Full Name
    carboxypeptidase A2provided by CGNC
    Primary source
    CGNC:50320
    See related
    Ensembl:ENSGALG00010006552
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See CPA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (1486907..1496412)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (1493666..1503171)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene putative cation exchanger C521.04c-like Neighboring gene transmembrane protein 209 Neighboring gene carboxypeptidase A5 Neighboring gene carboxypeptidase A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carboxypeptidase A2
    Names
    carboxypeptidase A2 (pancreatic)
    NP_001244143.1
    XP_015138595.2
    XP_015138634.2
    XP_046762966.1
    XP_046762967.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257214.1 → NP_001244143.1  carboxypeptidase A2 precursor

      Status: PROVISIONAL

      Source sequence(s)
      BX935350
      UniProtKB/TrEMBL
      A0A8V0XSY3
      Related
      ENSGALP00010009081.1, ENSGALT00010015595.1
      Conserved Domains (2) summary
      cd03870
      Location:117 → 417
      M14_CPA; Peptidase M14 carboxypeptidase subfamily A/B-like; Carboxypeptidase A subgroup
      pfam02244
      Location:27 → 99
      Propep_M14; Carboxypeptidase activation peptide

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1486907..1496412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015283109.3 → XP_015138595.2  carboxypeptidase A2 isoform X1

      Conserved Domains (1) summary
      cd03870
      Location:211 → 511
      M14_CPA; Peptidase M14 carboxypeptidase subfamily A/B-like; Carboxypeptidase A subgroup

    2. XM_015283148.3 → XP_015138634.2  carboxypeptidase A2 isoform X2

      Conserved Domains (1) summary
      cd03870
      Location:190 → 490
      M14_CPA; Peptidase M14 carboxypeptidase subfamily A/B-like; Carboxypeptidase A subgroup

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1493666..1503171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046907010.1 → XP_046762966.1  carboxypeptidase A2 isoform X3

    2. XM_046907011.1 → XP_046762967.1  carboxypeptidase A2 isoform X4

    Nucleotide Protein
    Heading Accession and Version

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