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    SYT1 synaptotagmin 1 [ Gallus gallus (chicken) ]

    Gene ID: 396083, updated on 3-Dec-2024

    Summary

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    Symbol
    SYT1provided by CGNC
    Full Name
    synaptotagmin 1provided by CGNC
    Primary source
    CGNC:7852
    See related
    Ensembl:ENSGALG00010012026
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    synaptotagmin-1
    Orthologs
    human mouse all
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    Genomic context

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    See SYT1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (39200929..39547338)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (39544505..39890500)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene neuron navigator 3 Neighboring gene neuron navigator 1-like Neighboring gene uncharacterized LOC101749434 Neighboring gene uncharacterized LOC121109500 Neighboring gene pro-apoptotic WT1 regulator Neighboring gene protein phosphatase 1 regulatory subunit 12A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synaptotagmin-1 promotes the formation of axonal filopodia and branches along the developing axons of forebrain neurons. Greif KF, et al. Dev Neurobiol, 2013 Jan. PMID 22589224
    2. Coordinate and noncoordinate regulation of synaptic vesicle protein genes during embryonic development. Lou X, et al. Dev Biol, 1993 Sep. PMID 8365570
    3. 'Fractional recovery' analysis of a presynaptic synaptotagmin 1-anchored endocytic protein complex. Khanna R, et al. PLoS One, 2006 Dec 20. PMID 17183698, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables clathrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylserine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion-regulated exocytosis of neurotransmitter IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of calcium ion-dependent exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dopamine secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dense core granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    synaptotagmin-1
    Names
    p65
    synaptotagmin I
    synaptotagmin p65
    sytI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396953.1 → NP_001383882.1  synaptotagmin-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5
      Conserved Domains (3) summary
      cd08385
      Location:145 → 267
      C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
      cd08402
      Location:276 → 411
      C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
      cd21963
      Location:6 → 115
      Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins

    2. NM_001396954.1 → NP_001383883.1  synaptotagmin-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5
      Conserved Domains (3) summary
      cd08385
      Location:145 → 267
      C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
      cd08402
      Location:276 → 411
      C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
      cd21963
      Location:6 → 115
      Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins

    3. NM_205171.2 → NP_990502.1  synaptotagmin-1

      See identical proteins and their annotated locations for NP_990502.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5
      Related
      ENSGALP00010016573.1, ENSGALT00010028805.1
      Conserved Domains (3) summary
      cd08385
      Location:145 → 267
      C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
      cd08402
      Location:276 → 411
      C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
      cd21963
      Location:6 → 115
      Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      39200929..39547338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046914478.1 → XP_046770434.1  synaptotagmin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YKI5

    2. XM_046914451.1 → XP_046770407.1  synaptotagmin-1 isoform X1

      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5

    3. XM_046914489.1 → XP_046770445.1  synaptotagmin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YKI5

    4. XM_046914473.1 → XP_046770429.1  synaptotagmin-1 isoform X1

      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      39544505..39890500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046906785.1 → XP_046762741.1  synaptotagmin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YKI5

    2. XM_046906783.1 → XP_046762739.1  synaptotagmin-1 isoform X1

      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5

    3. XM_046906786.1 → XP_046762742.1  synaptotagmin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YKI5

    4. XM_046906784.1 → XP_046762740.1  synaptotagmin-1 isoform X1

      UniProtKB/Swiss-Prot
      P47191
      UniProtKB/TrEMBL
      A0A8V0YKI5
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47191.1 GenPept UniProtKB/Swiss-Prot:P47191

    Gene LinkOut

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