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    DENND6A DENN domain containing 6A [ Gallus gallus (chicken) ]

    Gene ID: 416006, updated on 3-Dec-2024

    Summary

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    Symbol
    DENND6Aprovided by CGNC
    Full Name
    DENN domain containing 6Aprovided by CGNC
    Primary source
    CGNC:50136
    See related
    Ensembl:ENSGALG00010027083
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    FAM116A
    Orthologs
    human mouse all
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    Genomic context

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    See DENND6A in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (8915590..8940236, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (8942872..8967526, complement)

    Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 12 Neighboring gene ADP ribosylation factor 4 Neighboring gene uncharacterized LOC121106678 Neighboring gene microRNA 1787 Neighboring gene sarcolemma associated protein Neighboring gene filamin B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in recycling endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein DENND6A
    Names
    DENN domain-containing protein 6A
    DENN/MADD domain containing 6A
    family with sequence similarity 116, member A
    protein FAM116A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012781.2 → NP_001012799.2  protein DENND6A

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000252
      UniProtKB/Swiss-Prot
      Q5F3L4
      UniProtKB/TrEMBL
      A0A1D5NY14
      Related
      ENSGALP00010039910.1, ENSGALT00010065644.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      8915590..8940236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025154466.3 → XP_025010234.1  protein DENND6A isoform X2

      UniProtKB/Swiss-Prot
      Q5F3L4
      UniProtKB/TrEMBL
      A0A8V1A713
      Related
      ENSGALP00010039915.1, ENSGALT00010065649.1
      Conserved Domains (1) summary
      pfam08616
      Location:201 → 307
      SPA; Stabilization of polarity axis

    2. XM_025154464.3 → XP_025010232.3  protein DENND6A isoform X1

      UniProtKB/Swiss-Prot
      Q5F3L4
      UniProtKB/TrEMBL
      A0A8V1A201
      Related
      ENSGALP00010039913.1, ENSGALT00010065647.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      8942872..8967526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046926305.1 → XP_046782261.1  protein DENND6A isoform X2

      UniProtKB/Swiss-Prot
      Q5F3L4
      UniProtKB/TrEMBL
      A0A8V1A713

    2. XM_046926304.1 → XP_046782260.1  protein DENND6A isoform X1

      UniProtKB/Swiss-Prot
      Q5F3L4
      UniProtKB/TrEMBL
      A0A8V1A201
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F3L4.1 GenPept UniProtKB/Swiss-Prot:Q5F3L4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials