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    CASK calcium/calmodulin dependent serine protein kinase [ Gallus gallus (chicken) ]

    Gene ID: 418565, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CASKprovided by CGNC
    Official Full Name
    calcium/calmodulin dependent serine protein kinaseprovided by CGNC
    Primary source
    CGNC:12132
    See related
    Ensembl:ENSGALG00010002424
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CASK in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (111886733..112082128)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (111940517..112136322)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101749987 Neighboring gene uncharacterized LOC112531051 Neighboring gene uncharacterized LOC101750030 Neighboring gene G protein-coupled receptor 82 Neighboring gene G protein-coupled receptor 34 Neighboring gene uncharacterized LOC121109949 Neighboring gene uncharacterized LOC101750611 Neighboring gene nyctalopin Neighboring gene DEAD-box helicase 3X

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurotransmitter secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peripheral plasma membrane protein CASK
    Names
    calcium/calmodulin-dependent serine protein kinase (MAGUK family)
    XP_015157125.1
    XP_015157131.1
    XP_015157135.1
    XP_015157141.1
    XP_015157146.1
    XP_025001723.1
    XP_025001724.1
    XP_025001725.1
    XP_025001726.1
    XP_025001733.1
    XP_025001737.1
    XP_025001743.1
    XP_040517710.1
    XP_040517711.1
    XP_040517712.1
    XP_040517713.1
    XP_040517714.1
    XP_040517715.1
    XP_040517716.1
    XP_040517717.1
    XP_040517718.1
    XP_040517719.1
    XP_040517720.1
    XP_040517721.1
    XP_040517722.1
    XP_040520802.1
    XP_046765792.1
    XP_046767419.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      111886733..112082128
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015301649.4 → XP_015157135.1  peripheral plasma membrane protein CASK isoform X1

      UniProtKB/TrEMBL
      A0A1D5PB73, A0A8V0X9W6
      Related
      ENSGALP00010003425.1, ENSGALT00010005586.1
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 911
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    2. XM_015301645.4 → XP_015157131.1  peripheral plasma membrane protein CASK isoform X2

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:733 → 906
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    3. XM_025145956.3 → XP_025001724.1  peripheral plasma membrane protein CASK isoform X4

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:604 → 665
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:726 → 899
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    4. XM_025145957.3 → XP_025001725.1  peripheral plasma membrane protein CASK isoform X5

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:604 → 665
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:721 → 894
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    5. XM_025145958.3 → XP_025001726.1  peripheral plasma membrane protein CASK isoform X7

      UniProtKB/TrEMBL
      A0A8V0X9W6, A0A8V0XCV3
      Related
      ENSGALP00010003422.1, ENSGALT00010005583.1
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:715 → 888
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    6. XM_015301655.4 → XP_015157141.1  peripheral plasma membrane protein CASK isoform X8

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:710 → 883
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    7. XM_025145965.3 → XP_025001733.1  peripheral plasma membrane protein CASK isoform X10

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:581 → 642
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:703 → 876
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    8. XM_025145955.3 → XP_025001723.1  peripheral plasma membrane protein CASK isoform X3

      UniProtKB/TrEMBL
      A0A3Q2UPZ2, A0A8V0X9W6
      Related
      ENSGALP00010003429.1, ENSGALT00010005590.1
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 905
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    9. XM_040664868.2 → XP_040520802.1  peripheral plasma membrane protein CASK isoform X6

      UniProtKB/TrEMBL
      A0A8V0X5T9, A0A8V0X9W6
      Related
      ENSGALP00010003430.1, ENSGALT00010005591.1
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:598 → 659
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:720 → 893
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    10. XM_015301660.4 → XP_015157146.1  peripheral plasma membrane protein CASK isoform X9

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 882
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    11. XM_025145969.3 → XP_025001737.1  peripheral plasma membrane protein CASK isoform X11

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Related
      ENSGALP00010003433.1, ENSGALT00010005594.1
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:575 → 636
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:692 → 865
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    12. XM_025145975.2 → XP_025001743.1  peripheral plasma membrane protein CASK isoform X12

      Conserved Domains (6) summary
      smart00569
      Location:163 → 216
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12035
      Location:431 → 492
      SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
      cd00992
      Location:303 → 383
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:553 → 726
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:221 → 271
      L27; L27 domain
      cl21453
      Location:1 → 122
      PKc_like; Protein Kinases, catalytic domain

    13. XM_046911463.1 → XP_046767419.1  peripheral plasma membrane protein CASK isoform X13

    14. XM_015301639.4 → XP_015157125.1  peripheral plasma membrane protein CASK isoform X13

      Conserved Domains (3) summary
      cd12035
      Location:179 → 240
      SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
      cd00992
      Location:51 → 131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:301 → 474
      Guanylate_kin; Guanylate kinase

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      111940517..112136322
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040661776.2 → XP_040517710.1  peripheral plasma membrane protein CASK isoform X1

      UniProtKB/TrEMBL
      A0A1D5PB73, A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 911
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    2. XM_040661777.2 → XP_040517711.1  peripheral plasma membrane protein CASK isoform X2

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:733 → 906
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    3. XM_040661779.2 → XP_040517713.1  peripheral plasma membrane protein CASK isoform X4

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:604 → 665
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:726 → 899
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    4. XM_040661780.2 → XP_040517714.1  peripheral plasma membrane protein CASK isoform X5

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:604 → 665
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:721 → 894
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    5. XM_040661782.2 → XP_040517716.1  peripheral plasma membrane protein CASK isoform X7

      UniProtKB/TrEMBL
      A0A8V0X9W6, A0A8V0XCV3
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:715 → 888
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    6. XM_040661783.2 → XP_040517717.1  peripheral plasma membrane protein CASK isoform X8

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:710 → 883
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    7. XM_040661785.2 → XP_040517719.1  peripheral plasma membrane protein CASK isoform X10

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:581 → 642
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:703 → 876
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    8. XM_040661778.2 → XP_040517712.1  peripheral plasma membrane protein CASK isoform X3

      UniProtKB/TrEMBL
      A0A3Q2UPZ2, A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 905
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    9. XM_040661781.2 → XP_040517715.1  peripheral plasma membrane protein CASK isoform X6

      UniProtKB/TrEMBL
      A0A8V0X5T9, A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:598 → 659
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:720 → 893
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    10. XM_040661784.2 → XP_040517718.1  peripheral plasma membrane protein CASK isoform X9

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 882
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    11. XM_040661786.2 → XP_040517720.1  peripheral plasma membrane protein CASK isoform X11

      UniProtKB/TrEMBL
      A0A8V0X9W6
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:575 → 636
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:692 → 865
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    12. XM_040661787.1 → XP_040517721.1  peripheral plasma membrane protein CASK isoform X12

      Conserved Domains (6) summary
      smart00569
      Location:163 → 216
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12035
      Location:431 → 492
      SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
      cd00992
      Location:303 → 383
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:553 → 726
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:221 → 271
      L27; L27 domain
      cl21453
      Location:1 → 122
      PKc_like; Protein Kinases, catalytic domain

    13. XM_046909836.1 → XP_046765792.1  peripheral plasma membrane protein CASK isoform X13

    14. XM_040661788.2 → XP_040517722.1  peripheral plasma membrane protein CASK isoform X13

      Conserved Domains (3) summary
      cd12035
      Location:179 → 240
      SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
      cd00992
      Location:51 → 131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:301 → 474
      Guanylate_kin; Guanylate kinase
    Nucleotide Protein
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