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    MAEA macrophage erythroblast attacher [ Gallus gallus (chicken) ]

    Gene ID: 426024, updated on 3-Dec-2024

    Summary

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    Symbol
    MAEAprovided by CGNC
    Full Name
    macrophage erythroblast attacherprovided by CGNC
    Primary source
    CGNC:52649
    See related
    Ensembl:ENSGALG00010017646
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MAEA in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (84004148..84050360, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (83983165..84029060, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene UV stimulated scaffold protein A Neighboring gene uncharacterized LOC121113230 Neighboring gene C-terminal binding protein 1 Neighboring gene spondin 2 Neighboring gene uncharacterized LOC121110769

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GID complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein transferase MAEA
    NP_001012622.1
    XP_015141409.3
    XP_015141410.1
    XP_015141411.1
    XP_040555012.1
    XP_046772409.1
    XP_046772410.1
    XP_046772411.1
    XP_046772412.1
    XP_046772413.1
    XP_046772414.1
    XP_046772415.1
    XP_046796234.1
    XP_046796235.1
    XP_046796236.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012604.2 → NP_001012622.1  E3 ubiquitin-protein transferase MAEA

      See identical proteins and their annotated locations for NP_001012622.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000074
      UniProtKB/Swiss-Prot
      Q5F398
      UniProtKB/TrEMBL
      A0A8V0Z2I8
      Related
      ENSGALP00010025136.1, ENSGALT00010042646.1
      Conserved Domains (3) summary
      smart00667
      Location:120 → 153
      LisH; Lissencephaly type-1-like homology motif
      cd16659
      Location:336 → 383
      RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
      pfam10607
      Location:160 → 301
      CLTH; CTLH/CRA C-terminal to LisH motif domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      84004148..84050360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015285923.4 → XP_015141409.3  E3 ubiquitin-protein transferase MAEA isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z2I8
      Conserved Domains (3) summary
      smart00667
      Location:112 → 145
      LisH; Lissencephaly type-1-like homology motif
      cd16659
      Location:328 → 375
      RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
      pfam10607
      Location:152 → 293
      CLTH; CTLH/CRA C-terminal to LisH motif domain

    2. XM_046940278.1 → XP_046796234.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    3. XM_015285925.4 → XP_015141411.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8
      Related
      ENSGALP00010025133.1, ENSGALT00010042643.1
      Conserved Domains (3) summary
      smart00667
      Location:72 → 105
      LisH; Lissencephaly type-1-like homology motif
      cd16659
      Location:288 → 335
      RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
      pfam10607
      Location:112 → 253
      CLTH; CTLH/CRA C-terminal to LisH motif domain

    4. XM_015285924.4 → XP_015141410.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8
      Conserved Domains (3) summary
      smart00667
      Location:72 → 105
      LisH; Lissencephaly type-1-like homology motif
      cd16659
      Location:288 → 335
      RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
      pfam10607
      Location:112 → 253
      CLTH; CTLH/CRA C-terminal to LisH motif domain

    5. XM_046940280.1 → XP_046796236.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    6. XM_046940279.1 → XP_046796235.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    7. XM_040699078.2 → XP_040555012.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8
      Conserved Domains (3) summary
      smart00667
      Location:72 → 105
      LisH; Lissencephaly type-1-like homology motif
      cd16659
      Location:288 → 335
      RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
      pfam10607
      Location:112 → 253
      CLTH; CTLH/CRA C-terminal to LisH motif domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      83983165..84029060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916453.1 → XP_046772409.1  E3 ubiquitin-protein transferase MAEA isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    2. XM_046916457.1 → XP_046772413.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    3. XM_046916456.1 → XP_046772412.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    4. XM_046916454.1 → XP_046772410.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    5. XM_046916459.1 → XP_046772415.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    6. XM_046916458.1 → XP_046772414.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8

    7. XM_046916455.1 → XP_046772411.1  E3 ubiquitin-protein transferase MAEA isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z2I8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F398.1 GenPept UniProtKB/Swiss-Prot:Q5F398

    Gene LinkOut

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