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    LOC420419 mitogen-activated protein kinase kinase kinase 3-like [ Gallus gallus (chicken) ]

    Gene ID: 420419, updated on 3-Dec-2024

    Summary

    Symbol
    LOC420419provided by CGNC
    Full Name
    mitogen-activated protein kinase kinase kinase 3-likeprovided by CGNC
    Primary source
    CGNC:51255
    See related
    Ensembl:ENSGALG00010026516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    MAPKKK3L
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    Genomic context

    See LOC420419 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (4733026..4801287, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (4735504..4803796, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene deleted in lung and esophageal cancer 1 Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene uncharacterized LOC121112363 Neighboring gene myeloid differentiation primary response 88

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    mitogen-activated protein kinase kinase kinase 3-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079726.2NP_001073194.1  mitogen-activated protein kinase kinase kinase 3-like

      See identical proteins and their annotated locations for NP_001073194.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000035
      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
      Related
      ENSGALP00010039540.1, ENSGALT00010064459.1
      Conserved Domains (3) summary
      cd06405
      Location:42120
      PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
      smart00220
      Location:357617
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06653
      Location:354617
      STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4733026..4801287 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015281099.4XP_015136585.1  mitogen-activated protein kinase kinase kinase 3-like isoform X2

      UniProtKB/TrEMBL
      A0A8V1A8I7
      Conserved Domains (3) summary
      cd06405
      Location:41119
      PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
      smart00220
      Location:356616
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06653
      Location:353616
      STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases
    2. XM_046921373.1XP_046777329.1  mitogen-activated protein kinase kinase kinase 3-like isoform X4

      UniProtKB/TrEMBL
      A0A8V1A8I7
    3. XM_046921371.1XP_046777327.1  mitogen-activated protein kinase kinase kinase 3-like isoform X3

      UniProtKB/TrEMBL
      A0A8V1A8I3, A0A8V1A8I7
      Related
      ENSGALP00010039536.1, ENSGALT00010064451.1
    4. XM_046921353.1XP_046777309.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
    5. XM_046921362.1XP_046777318.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
    6. XM_015281097.4XP_015136583.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
      Conserved Domains (3) summary
      cd06405
      Location:42120
      PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
      smart00220
      Location:357617
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06653
      Location:354617
      STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4735504..4803796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046910875.1XP_046766831.1  mitogen-activated protein kinase kinase kinase 3-like isoform X2

      UniProtKB/TrEMBL
      A0A8V1A8I7
    2. XM_046910877.1XP_046766833.1  mitogen-activated protein kinase kinase kinase 3-like isoform X4

      UniProtKB/TrEMBL
      A0A8V1A8I7
    3. XM_046910876.1XP_046766832.1  mitogen-activated protein kinase kinase kinase 3-like isoform X3

      UniProtKB/TrEMBL
      A0A8V1A8I3, A0A8V1A8I7
    4. XM_046910873.1XP_046766829.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
    5. XM_046910874.1XP_046766830.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4
    6. XM_046910872.1XP_046766828.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8I7, F1NAY6, Q5ZLW4

    RNA

    1. XR_006933396.1 RNA Sequence