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    WDR59 WD repeat domain 59 [ Gallus gallus (chicken) ]

    Gene ID: 415688, updated on 3-Dec-2024

    Summary

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    Symbol
    WDR59provided by CGNC
    Full Name
    WD repeat domain 59provided by CGNC
    Primary source
    CGNC:2018
    See related
    Ensembl:ENSGALG00010023335
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See WDR59 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (1922165..1970763, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (2094572..2143168, complement)

    Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene mixed lineage kinase domain like pseudokinase Neighboring gene fatty acid 2-hydroxylase Neighboring gene microRNA 1643 Neighboring gene zinc and ring finger 1 Neighboring gene lactate dehydrogenase D Neighboring gene chymotrypsinogen B1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GATOR2 complex protein WDR59; GATOR complex protein WDR59
    Names
    WD repeat-containing protein 59

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012776.2 → NP_001012794.1  GATOR2 complex protein WDR59

      See identical proteins and their annotated locations for NP_001012794.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000247
      UniProtKB/Swiss-Prot
      Q5ZLG9
      UniProtKB/TrEMBL
      A0A8V0ZUT0
      Related
      ENSGALP00010034599.1, ENSGALT00010056900.1
      Conserved Domains (5) summary
      COG2319
      Location:34 → 340
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:62 → 103
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:101 → 319
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl02687
      Location:394 → 493
      RWD; RWD domain
      cl24077
      Location:923 → 971
      Zn_ribbon_17; Zinc-ribbon, C4HC2 type

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1922165..1970763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015279138.4 → XP_015134624.1  GATOR complex protein WDR59 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZMI1, A0A8V0ZUT0
      Related
      ENSGALP00010034595.1, ENSGALT00010056888.1
      Conserved Domains (5) summary
      COG2319
      Location:34 → 340
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:62 → 103
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:101 → 319
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl02687
      Location:394 → 493
      RWD; RWD domain
      cl24077
      Location:942 → 990
      Zn_ribbon_17; Zinc-ribbon, C4HC2 type

    2. XM_025154156.3 → XP_025009924.1  GATOR complex protein WDR59 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZSR1, A0A8V0ZUT0
      Related
      ENSGALP00010034592.1, ENSGALT00010056884.1
      Conserved Domains (4) summary
      COG2319
      Location:36 → 342
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16692
      Location:923 → 969
      mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins
      cl02687
      Location:396 → 495
      RWD; RWD domain

    3. XM_040707043.2 → XP_040562977.1  GATOR complex protein WDR59 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZUT0
      Conserved Domains (4) summary
      COG2319
      Location:36 → 342
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16692
      Location:942 → 988
      mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins
      cl02687
      Location:396 → 495
      RWD; RWD domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2094572..2143168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046925439.1 → XP_046781395.1  GATOR complex protein WDR59 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZMI1, A0A8V0ZUT0

    2. XM_046925440.1 → XP_046781396.1  GATOR complex protein WDR59 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZSR1, A0A8V0ZUT0

    3. XM_046925438.1 → XP_046781394.1  GATOR complex protein WDR59 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZUT0
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZLG9.1 GenPept UniProtKB/Swiss-Prot:Q5ZLG9

    Gene LinkOut

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