U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PROM1 prominin 1 [ Gallus gallus (chicken) ]

    Gene ID: 422825, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Symbol
    PROM1provided by CGNC
    Full Name
    prominin 1provided by CGNC
    Primary source
    CGNC:10775
    See related
    Ensembl:ENSGALG00010010434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    prominin-1
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PROM1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (76039401..76098578)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (76016824..76076214)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417920 Neighboring gene transmembrane anterior posterior transformation 1 Neighboring gene uncharacterized LOC121110788 Neighboring gene uncharacterized LOC107053291 Neighboring gene fibroblast growth factor binding protein 2 Neighboring gene fibroblast growth factor binding protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species. Jászai J, et al. PLoS One, 2011 Mar 2. PMID 21407811, Free PMC Article
    2. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
    3. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microvillus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in prominosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    prominin-1
    Names
    prominin-1.s11
    prominin-1.s16
    prominin-1.s17
    prominin-1.s7

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291649.2 → NP_001278578.1  prominin-1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001278578.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), also known as s17, represents the longest transcript and encodes the longest protein (isoform 1).
      Source sequence(s)
      JAENSK010000074
      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE8
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 825
      Prominin; Prominin

    2. NM_001291651.2 → NP_001278580.1  prominin-1 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001278580.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), also known as s16, lacks two alternate in-frame exons compared to variant 1. The encoded protein (isoform 2) is shorter compared to isoform 1.
      Source sequence(s)
      JAENSK010000074
      UniProtKB/TrEMBL
      A0A8V0Y5F0, F1CLF0, R4GGA3
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 813
      Prominin; Prominin

    3. NM_001291652.2 → NP_001278581.1  prominin-1 isoform 3 precursor

      See identical proteins and their annotated locations for NP_001278581.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), also known as s11, lacks an alternate in-frame exon in the 5' CDS and one in the 3' CDS compared to variant 1. The encoded protein (isoform 3) is shorter compared to isoform 1.
      Source sequence(s)
      JAENSK010000074
      UniProtKB/TrEMBL
      A0A8V0Y0X2, F1CLE7, R4GHW6
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 822
      Prominin; Prominin

    4. NM_001291653.2 → NP_001278582.1  prominin-1 isoform 4 precursor

      See identical proteins and their annotated locations for NP_001278582.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), also known as s7, lacks three alternate in-frame exons compared to variant 1. The encoded protein (isoform 4) is shorter compared to isoform 1.
      Source sequence(s)
      JAENSK010000074
      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE9
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 813
      Prominin; Prominin

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      76039401..76098578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040699032.2 → XP_040554966.1  prominin-1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Related
      ENSGALP00010014177.1, ENSGALT00010024960.1
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin

    2. XM_015285739.4 → XP_015141225.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin

    3. XM_015285744.4 → XP_015141230.1  prominin-1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin; Prominin

    4. XM_015285749.4 → XP_015141235.1  prominin-1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Related
      ENSGALP00010014208.1, ENSGALT00010025001.1
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin

    5. XM_015285742.4 → XP_015141228.1  prominin-1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y5I3
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 825
      Prominin; Prominin

    6. XM_015285747.4 → XP_015141233.1  prominin-1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE8
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 825
      Prominin; Prominin

    7. XM_025149701.3 → XP_025005469.1  prominin-1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0Y5I3
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 825
      Prominin

    8. XM_015285741.4 → XP_015141227.1  prominin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 828
      Prominin; Prominin

    9. XM_004936154.5 → XP_004936211.1  prominin-1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Y0X2, E1C9E2
      Related
      ENSGALP00010014203.1, ENSGALT00010024995.1
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 822
      Prominin; Prominin

    10. XM_015285745.4 → XP_015141231.1  prominin-1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y5F0
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 822
      Prominin

    11. XM_004936155.5 → XP_004936212.1  prominin-1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Y5F0, A0A8V0Y739
      Related
      ENSGALP00010014195.1, ENSGALT00010024985.1
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 813
      Prominin; Prominin

    12. XM_015285748.4 → XP_015141234.1  prominin-1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Y5F0, F1CLF0, R4GGA3
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 813
      Prominin; Prominin

    13. XM_015285751.4 → XP_015141237.1  prominin-1 isoform X14

      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE9
      Related
      ENSGALP00010014212.1, ENSGALT00010025007.1
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 813
      Prominin; Prominin

    14. XM_015285753.4 → XP_015141239.1  prominin-1 isoform X15

      UniProtKB/TrEMBL
      A0A8V0Y5F0
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 713
      Prominin; Prominin

    15. XM_040699033.2 → XP_040554967.1  prominin-1 isoform X16

      UniProtKB/TrEMBL
      A0A8V0Y5I3

    16. XM_040699031.2 → XP_040554965.1  prominin-1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    17. XM_046940194.1 → XP_046796150.1  prominin-1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Y0X2, F1CLE7, R4GHW6

    18. XM_040699029.2 → XP_040554963.1  prominin-1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y5F0
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 822
      Prominin

    19. XM_025149700.3 → XP_025005468.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin

    20. XM_040699028.2 → XP_040554962.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2
      Conserved Domains (1) summary
      pfam05478
      Location:27 → 831
      Prominin

    RNA

    1. XR_003074738.3 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      76016824..76076214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916297.1 → XP_046772253.1  prominin-1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    2. XM_046916284.1 → XP_046772240.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    3. XM_046916291.1 → XP_046772247.1  prominin-1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y5F0

    4. XM_046916283.1 → XP_046772239.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    5. XM_046916288.1 → XP_046772244.1  prominin-1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    6. XM_046916296.1 → XP_046772252.1  prominin-1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    7. XM_046916287.1 → XP_046772243.1  prominin-1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y5I3

    8. XM_046916292.1 → XP_046772248.1  prominin-1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE8

    9. XM_046916298.1 → XP_046772254.1  prominin-1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0Y5I3

    10. XM_046916286.1 → XP_046772242.1  prominin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    11. XM_046916289.1 → XP_046772245.1  prominin-1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Y0X2, E1C9E2

    12. XM_046916299.1 → XP_046772255.1  prominin-1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Y0X2, F1CLE7, R4GHW6

    13. XM_046916290.1 → XP_046772246.1  prominin-1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y5F0

    14. XM_046916294.1 → XP_046772250.1  prominin-1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Y5F0, A0A8V0Y739

    15. XM_046916295.1 → XP_046772251.1  prominin-1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Y5F0, F1CLF0, R4GGA3

    16. XM_046916300.1 → XP_046772256.1  prominin-1 isoform X14

      UniProtKB/TrEMBL
      A0A8V0Y5I3, F1CLE9

    17. XM_046916301.1 → XP_046772257.1  prominin-1 isoform X15

      UniProtKB/TrEMBL
      A0A8V0Y5F0

    18. XM_046916302.1 → XP_046772258.1  prominin-1 isoform X16

      UniProtKB/TrEMBL
      A0A8V0Y5I3

    19. XM_046916293.1 → XP_046772249.1  prominin-1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    20. XM_046916285.1 → XP_046772241.1  prominin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0X2

    RNA

    1. XR_006934379.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031162.1: Suppressed sequence

      Description
      NM_001031162.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials