LAMA1 laminin subunit alpha 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: LAMA1provided by CGNC
Full Name: laminin subunit alpha 1provided by CGNC
Primary source: CGNC:10834
See related: Ensembl:ENSGALG00010001967
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 63

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (99141265..99240471)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (99200734..99299926)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Integrin-Linked Kinase (ILK) Plays an Important Role in the Laminin-Dependent Development of Dorsal Root Ganglia during Chicken Embryogenesis.
Title: Integrin-Linked Kinase (ILK) Plays an Important Role in the Laminin-Dependent Development of Dorsal Root Ganglia during Chicken Embryogenesis.
Loss of Draxin results in blocking laminin remodeling at the regression stage.
Title: Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT.
The distribution of laminin and alphaSMA in the testis and epididymis might point out to their roles in the male reproduction.
Title: Comparative expression of laminin and smooth muscle actin in the testis and epididymis of poultry and rabbit.
laminin-1 may be involved in axonal guidance of DRG neurons
Title: Laminin peptide YIGSR and its receptor regulate sensory axonal response to the chemoattractive guidance cue in the chick embryo.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables extracellular matrix structural constituent	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in blood vessel morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in camera-type eye development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of embryonic development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in basement membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: laminin subunit alpha-1

Names: laminin, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199806.2 → NP_001186735.2 laminin subunit alpha-1 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000043

UniProtKB/TrEMBL

A0A8V0X4B2