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    PIAS2 protein inhibitor of activated STAT 2 [ Gallus gallus (chicken) ]

    Gene ID: 416383, updated on 3-Dec-2024

    Summary

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    Symbol
    PIAS2provided by CGNC
    Full Name
    protein inhibitor of activated STAT 2provided by CGNC
    Primary source
    CGNC:50239
    See related
    Ensembl:ENSGALG00010009774
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PIAS2 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (2117366..2144821)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (2117366..2144821)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene immediate early response 3 interacting protein 1 Neighboring gene haloacid dehalogenase like hydrolase domain containing 2 Neighboring gene katanin catalytic subunit A1 like 2 Neighboring gene uncharacterized LOC107051906 Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Neighboring gene lipoxygenase homology domains 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 SUMO-protein ligase PIAS2
    NP_001025797.1
    XP_015132766.1
    XP_015132767.1
    XP_015132769.1
    XP_046761249.1
    XP_046761250.1
    XP_046790899.1
    XP_046790900.1
    XP_046790901.1
    XP_046790903.1
    XP_046790904.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030626.2 → NP_001025797.1  E3 SUMO-protein ligase PIAS2

      See identical proteins and their annotated locations for NP_001025797.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000086
      UniProtKB/TrEMBL
      A0A8V0Y7G0, F1NFQ6, Q5ZIN4
      Related
      ENSGALP00010013526.1, ENSGALT00010023416.1
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:342 → 390
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:145 → 282
      PINIT; PINIT domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2117366..2144821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015277280.3 → XP_015132766.1  E3 SUMO-protein ligase PIAS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y7G0
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:342 → 390
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:145 → 282
      PINIT; PINIT domain

    2. XM_015277281.3 → XP_015132767.1  E3 SUMO-protein ligase PIAS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y3I6, A0A8V0Y7G0
      Related
      ENSGALP00010013521.1, ENSGALT00010023406.1
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:342 → 390
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:145 → 282
      PINIT; PINIT domain

    3. XM_046905293.1 → XP_046761249.1  E3 SUMO-protein ligase PIAS2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    4. XM_046905294.1 → XP_046761250.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    5. XM_015277283.4 → XP_015132769.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y7G0
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:342 → 390
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:145 → 282
      PINIT; PINIT domain

    RNA

    1. XR_001463857.4 RNA Sequence

    2. XR_005842623.2 RNA Sequence

    3. XR_001463856.4 RNA Sequence

    4. XR_005842622.1 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2117366..2144821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046934943.1 → XP_046790899.1  E3 SUMO-protein ligase PIAS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    2. XM_046934944.1 → XP_046790900.1  E3 SUMO-protein ligase PIAS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y3I6, A0A8V0Y7G0

    3. XM_046934945.1 → XP_046790901.1  E3 SUMO-protein ligase PIAS2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    4. XM_046934948.1 → XP_046790904.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    5. XM_046934947.1 → XP_046790903.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y7G0

    RNA

    1. XR_006937422.1 RNA Sequence

    2. XR_006937420.1 RNA Sequence

    3. XR_006937421.1 RNA Sequence

    4. XR_006937419.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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