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    ELOVL6 ELOVL fatty acid elongase 6 [ Gallus gallus (chicken) ]

    Gene ID: 428772, updated on 3-Dec-2024

    Summary

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    Symbol
    ELOVL6provided by CGNC
    Full Name
    ELOVL fatty acid elongase 6provided by CGNC
    Primary source
    CGNC:53457
    See related
    Ensembl:ENSGALG00010003790
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ELOVL6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (57440736..57511280)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (57445104..57514368)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene glutamyl aminopeptidase Neighboring gene uncharacterized LOC121110595 Neighboring gene epidermal growth factor Neighboring gene leucine rich repeat, Ig-like and transmembrane domains 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver. Zhang DD, et al. Int J Mol Sci, 2020 Feb 27. PMID 32120850, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver.
      Title: Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid elongation, monounsaturated fatty acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid elongation, polyunsaturated fatty acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid elongation, saturated fatty acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingolipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in very long-chain fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    very long chain fatty acid elongase 6; elongation of very long chain fatty acids protein 6
    Names
    3-keto acyl-CoA synthase ELOVL6
    ELOVL FA elongase 6
    ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
    elongation of very long chain fatty acids family member protein 6
    very long chain 3-ketoacyl-CoA synthase 6
    very long chain 3-oxoacyl-CoA synthase 6
    NP_001026710.1
    XP_046772483.1
    XP_046772484.1
    XP_046772485.1
    XP_046796270.1
    XP_046796272.1
    XP_046796273.1
    XP_046796274.1
    XP_046796275.1
    XP_046796276.1
    XP_046796277.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031539.2 → NP_001026710.1  very long chain fatty acid elongase 6

      See identical proteins and their annotated locations for NP_001026710.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000074
      UniProtKB/Swiss-Prot
      Q5ZJR8
      UniProtKB/TrEMBL
      A0A8V0XLL5, E3VVZ9, F1NF61
      Related
      ENSGALP00010005129.1, ENSGALT00010008775.1
      Conserved Domains (1) summary
      pfam01151
      Location:25 → 261
      ELO; GNS1/SUR4 family

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      57440736..57511280
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046940314.1 → XP_046796270.1  elongation of very long chain fatty acids protein 6 isoform X1

    2. XM_046940316.1 → XP_046796272.1  elongation of very long chain fatty acids protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XLL5
      Related
      ENSGALP00010005128.1, ENSGALT00010008773.1

    3. XM_046940317.1 → XP_046796273.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7

    4. XM_046940319.1 → XP_046796275.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7

    5. XM_046940320.1 → XP_046796276.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7

    6. XM_046940318.1 → XP_046796274.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7

    7. XM_046940321.1 → XP_046796277.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      57445104..57514368
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916527.1 → XP_046772483.1  elongation of very long chain fatty acids protein 6 isoform X1

    2. XM_046916528.1 → XP_046772484.1  elongation of very long chain fatty acids protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XLL5

    3. XM_046916529.1 → XP_046772485.1  elongation of very long chain fatty acids protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEK7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZJR8.1 GenPept UniProtKB/Swiss-Prot:Q5ZJR8

    Gene LinkOut

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