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    PRKD1 protein kinase D1 [ Gallus gallus (chicken) ]

    Gene ID: 423302, updated on 3-Dec-2024

    Summary

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    Symbol
    PRKD1provided by CGNC
    Full Name
    protein kinase D1provided by CGNC
    Primary source
    CGNC:51946
    See related
    Ensembl:ENSGALG00010005458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PRKD1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (33326802..33441456, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (33303370..33418085, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC423301 Neighboring gene uncharacterized LOC124418023 Neighboring gene uncharacterized LOC101747910 Neighboring gene uncharacterized LOC107053509 Neighboring gene G2/M-phase specific E3 ubiquitin protein ligase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase D1
    NP_001026372.1
    NP_001384132.1
    NP_001384133.1
    NP_001384134.1
    XP_015142845.1
    XP_046774492.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031201.2 → NP_001026372.1  serine/threonine-protein kinase D1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A8V0XU96, Q5F3M9
      Related
      ENSGALP00010007583.1, ENSGALT00010013021.1
      Conserved Domains (5) summary
      smart00220
      Location:566 → 790
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00029
      Location:250 → 299
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01239
      Location:395 → 522
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:558 → 790
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      pfam00130
      Location:126 → 175
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

    2. NM_001397203.1 → NP_001384132.1  serine/threonine-protein kinase D1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A8V0XU91
      Related
      ENSGALP00010007589.1, ENSGALT00010013027.1
      Conserved Domains (4) summary
      cd01239
      Location:403 → 530
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:566 → 825
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20839
      Location:119 → 190
      C1_PKD1_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D (PKD) and similar proteins
      cd20842
      Location:224 → 317
      C1_PKD1_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D (PKD) and similar proteins

    3. NM_001397204.1 → NP_001384133.1  serine/threonine-protein kinase D1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A8V0XRQ6
      Related
      ENSGALP00010007591.1, ENSGALT00010013029.1
      Conserved Domains (4) summary
      cd01239
      Location:395 → 522
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:558 → 817
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20839
      Location:119 → 190
      C1_PKD1_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D (PKD) and similar proteins
      cd20842
      Location:216 → 309
      C1_PKD1_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D (PKD) and similar proteins

    4. NM_001397205.1 → NP_001384134.1  serine/threonine-protein kinase D1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A8V0XRQ6
      Conserved Domains (3) summary
      smart00109
      Location:175 → 224
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      cd01239
      Location:320 → 447
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:483 → 742
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      33326802..33441456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015287359.4 → XP_015142845.1  serine/threonine-protein kinase D1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XU91
      Conserved Domains (5) summary
      smart00220
      Location:499 → 751
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00029
      Location:183 → 232
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01239
      Location:328 → 455
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:491 → 750
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      pfam00130
      Location:51 → 100
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      33303370..33418085 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046918536.1 → XP_046774492.1  serine/threonine-protein kinase D1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XU91
    Nucleotide Protein Strain
    Heading Accession and Version

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