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    CCNF cyclin F [ Gallus gallus (chicken) ]

    Gene ID: 416749, updated on 17-Aug-2024

    Summary

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    Symbol
    CCNFprovided by CGNC
    Full Name
    cyclin Fprovided by CGNC
    Primary source
    CGNC:6992
    See related
    Ensembl:ENSGALG00010017595
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See CCNF in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (14263458..14276171)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (14383223..14395930)

    Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene C16orf59 homolog Neighboring gene uncharacterized LOC121106815 Neighboring gene transmembrane protein 100-like Neighboring gene vaccinia related kinase 3 Neighboring gene uncharacterized LOC107054657 Neighboring gene microRNA 1715 Neighboring gene uncharacterized LOC121106816

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel F-box domain containing cyclin F like gene is required for maintaining the genome stability and survival of chicken primordial germ cells. Lee BR, et al. FASEB J, 2020 Jan. PMID 31914591
    2. Digital gene expression profiling and validation study highlight Cyclin F as an important regulator for sperm motility of chickens. Sun Y, et al. Poult Sci, 2019 Oct 1. PMID 31329967
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the chicken cyclin F like gene, which is not reported in any other species, is required for maintaining the genome stability of germ cells
      Title: A novel F-box domain containing cyclin F like gene is required for maintaining the genome stability and survival of chicken primordial germ cells.
    2. In summary, the present study provides insight into the potential genetic regulation of sperm motility and highlighted the underlying pathways (Insulin resistance and FoxO signaling pathways) and important candidate genes such as CCNF.
      Title: Digital gene expression profiling and validation study highlight Cyclin F as an important regulator for sperm motility of chickens.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cell cycle phase transition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of cyclin-dependent protein kinase holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G2/mitotic-specific cyclin-F; cyclin-F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      14263458..14276171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_415043.8 → XP_415043.7  cyclin-F isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z3I0
      Related
      ENSGALP00010025031.1, ENSGALT00010042541.1
      Conserved Domains (2) summary
      smart00256
      Location:34 → 72
      FBOX; A Receptor for Ubiquitination Targets
      cl40454
      Location:193 → 448
      CYCLIN_SF; Cyclin box fold superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14383223..14395930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040683681.2 → XP_040539615.1  cyclin-F isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z3I0
      Conserved Domains (2) summary
      smart00256
      Location:34 → 72
      FBOX; A Receptor for Ubiquitination Targets
      cl40454
      Location:193 → 448
      CYCLIN_SF; Cyclin box fold superfamily

    2. XM_040683682.2 → XP_040539616.1  cyclin-F isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z3I0
      Conserved Domains (2) summary
      smart00256
      Location:108 → 146
      FBOX; A Receptor for Ubiquitination Targets
      cl40454
      Location:267 → 522
      CYCLIN_SF; Cyclin box fold superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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