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    HCLS1 hematopoietic cell-specific Lyn substrate 1 [ Gallus gallus (chicken) ]

    Gene ID: 426867, updated on 3-Dec-2024

    Summary

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    Symbol
    HCLS1provided by CGNC
    Full Name
    hematopoietic cell-specific Lyn substrate 1provided by CGNC
    Primary source
    CGNC:7430
    See related
    Ensembl:ENSGALG00010007408
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See HCLS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (495336..507494)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (605679..617881)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121113363 Neighboring gene guanylyl cyclase-activating protein 1-like Neighboring gene golgin B1 Neighboring gene olfactory receptor, family 9, subfamily Q, member 1 Neighboring gene NME/NM23 nucleoside diphosphate kinase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of polarized growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hematopoietic lineage cell-specific protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031401.2 → NP_001026572.1  hematopoietic lineage cell-specific protein

      See identical proteins and their annotated locations for NP_001026572.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000004
      UniProtKB/TrEMBL
      A0A8V0XXK6, F1NVS5, Q5ZMV0
      Related
      ENSGALP00010009760.1, ENSGALT00010017660.1
      Conserved Domains (2) summary
      cd12073
      Location:460 → 514
      SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
      pfam02218
      Location:193 → 228
      HS1_rep; Repeat in HS1/Cortactin

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      495336..507494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701184.2 → XP_040557118.1  hematopoietic lineage cell-specific protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XXK6, F1NVS5, Q5ZMV0
      Conserved Domains (2) summary
      cd12073
      Location:460 → 514
      SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
      pfam02218
      Location:193 → 228
      HS1_rep; Repeat in HS1/Cortactin

    2. XM_046942738.1 → XP_046798694.1  hematopoietic lineage cell-specific protein isoform X1

      UniProtKB/TrEMBL
      A0A8V0XST8, A0A8V0XXK6
      Related
      ENSGALP00010009761.1, ENSGALT00010017661.1

    3. XM_040701182.2 → XP_040557116.1  hematopoietic lineage cell-specific protein isoform X2

      UniProtKB/TrEMBL
      A0A8V0XXK6
      Conserved Domains (2) summary
      cd12073
      Location:462 → 516
      SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
      pfam02218
      Location:196 → 231
      HS1_rep; Repeat in HS1/Cortactin

    4. XM_040701186.2 → XP_040557120.1  hematopoietic lineage cell-specific protein isoform X4

      UniProtKB/TrEMBL
      A0A8V0XXK6
      Conserved Domains (1) summary
      cd12073
      Location:459 → 513
      SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      605679..617881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908533.1 → XP_046764489.1  hematopoietic lineage cell-specific protein isoform X1

      UniProtKB/TrEMBL
      A0A8V0XST8, A0A8V0XXK6

    2. XM_046908534.1 → XP_046764490.1  hematopoietic lineage cell-specific protein isoform X2

      UniProtKB/TrEMBL
      A0A8V0XXK6

    3. XM_046908537.1 → XP_046764493.1  hematopoietic lineage cell-specific protein isoform X4

      UniProtKB/TrEMBL
      A0A8V0XXK6

    4. XM_046908536.1 → XP_046764492.1  hematopoietic lineage cell-specific protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XXK6, F1NVS5, Q5ZMV0
    Nucleotide Protein Strain
    Heading Accession and Version

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