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    PXDN peroxidasin [ Gallus gallus (chicken) ]

    Gene ID: 421914, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PXDNprovided by CGNC
    Official Full Name
    peroxidasinprovided by CGNC
    Primary source
    CGNC:12255
    See related
    Ensembl:ENSGALG00010003388
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PXDN in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (92584281..92660208, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (92388403..92464309, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene thyroid peroxidase Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC121110256 Neighboring gene myelin transcription factor 1 like Neighboring gene uncharacterized LOC121110257

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxidasin homolog
    XP_004940554.2
    XP_040523438.1
    XP_040523439.1
    XP_419931.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      92584281..92660208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004940497.5 → XP_004940554.2  peroxidasin homolog isoform X2

      UniProtKB/TrEMBL
      A0A8V0XGC6
      Related
      ENSGALP00010004742.1, ENSGALT00010007900.1
      Conserved Domains (11) summary
      cd05745
      Location:421 → 494
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:517 → 585
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      cd09826
      Location:839 → 1278
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      pfam07679
      Location:317 → 404
      I-set; Immunoglobulin I-set domain
      sd00031
      Location:63 → 77
      LRR_1; leucine-rich repeat [structural motif]
      pfam00093
      Location:1395 → 1445
      VWC; von Willebrand factor type C domain
      pfam03098
      Location:716 → 1257
      An_peroxidase; Animal haem peroxidase
      pfam12799
      Location:109 → 148
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:110 → 169
      LRR_8; Leucine rich repeat
      cl11960
      Location:321 → 404
      Ig; Immunoglobulin domain
      cl15307
      Location:167 → 218
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    2. XM_419931.8 → XP_419931.4  peroxidasin homolog isoform X1

      UniProtKB/TrEMBL
      A0A8V0XDJ1
      Related
      ENSGALP00010004739.1, ENSGALT00010007896.1
      Conserved Domains (12) summary
      cd05745
      Location:445 → 518
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:541 → 609
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      cd09826
      Location:863 → 1302
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      pfam07679
      Location:341 → 428
      I-set; Immunoglobulin I-set domain
      sd00031
      Location:111 → 134
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:64 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00093
      Location:1419 → 1469
      VWC; von Willebrand factor type C domain
      pfam03098
      Location:740 → 1281
      An_peroxidase; Animal haem peroxidase
      pfam12799
      Location:109 → 150
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:110 → 169
      LRR_8; Leucine rich repeat
      cl11960
      Location:345 → 428
      Ig; Immunoglobulin domain
      cl15307
      Location:191 → 242
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      92388403..92464309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040667505.2 → XP_040523439.1  peroxidasin homolog isoform X2

      UniProtKB/TrEMBL
      A0A8V0XGC6
      Conserved Domains (9) summary
      cd05745
      Location:421 → 494
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:517 → 585
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      TIGR00864
      Location:140 → 251
      PCC; polycystin cation channel protein
      cd09826
      Location:839 → 1278
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      smart00410
      Location:323 → 404
      IG_like; Immunoglobulin like
      COG4886
      Location:61 → 169
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:63 → 77
      LRR_1; leucine-rich repeat [structural motif]
      pfam00093
      Location:1395 → 1445
      VWC; von Willebrand factor type C domain
      cd00096
      Location:334 → 338
      Ig; Ig strand B [structural motif]

    2. XM_040667504.2 → XP_040523438.1  peroxidasin homolog isoform X1

      UniProtKB/TrEMBL
      A0A8V0XDJ1
      Conserved Domains (10) summary
      cd05745
      Location:445 → 518
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:541 → 609
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      cd09826
      Location:863 → 1302
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      smart00409
      Location:251 → 333
      IG; Immunoglobulin
      smart00410
      Location:347 → 428
      IG_like; Immunoglobulin like
      COG4886
      Location:61 → 314
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:111 → 134
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:64 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00093
      Location:1419 → 1469
      VWC; von Willebrand factor type C domain
      cd00096
      Location:358 → 362
      Ig; Ig strand B [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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