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    PDE4C phosphodiesterase 4C [ Gallus gallus (chicken) ]

    Gene ID: 769860, updated on 3-Dec-2024

    Summary

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    Symbol
    PDE4Cprovided by CGNC
    Full Name
    phosphodiesterase 4Cprovided by CGNC
    Primary source
    CGNC:55593
    See related
    Ensembl:ENSGALG00010027314
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    PDE4A
    Orthologs
    human mouse all
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    Genomic context

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    See PDE4C in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (4430305..4437246)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (3992600..3999538)

    Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene proline-rich receptor-like protein kinase PERK2 Neighboring gene JunD proto-oncogene, AP-1 transcription factor subunit Neighboring gene RAB3A, member RAS oncogene family Neighboring gene MPV17 mitochondrial inner membrane protein like 2 Neighboring gene IFI30, lysosomal thiol reductase Neighboring gene phosphoinositide-3-kinase regulatory subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cAMP-specific 3',5'-cyclic phosphodiesterase 4C
    Names
    phosphodiesterase 4A, cAMP-specific

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4430305..4437246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015300157.4 → XP_015155643.3  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3

      UniProtKB/TrEMBL
      A0A8V1A8H6, A0A8V1AB62
      Related
      ENSGALP00010040479.1, ENSGALT00010066213.1
      Conserved Domains (1) summary
      cd00077
      Location:355 → 537
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    2. XM_015300158.4 → XP_015155644.3  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4

      UniProtKB/TrEMBL
      A0A8V1A3M2, A0A8V1A8H6
      Related
      ENSGALP00010040480.1, ENSGALT00010066214.1
      Conserved Domains (1) summary
      cd00077
      Location:355 → 537
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    3. XM_015300156.4 → XP_015155642.4  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

    4. XM_015300155.4 → XP_015155641.4  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8H6
      Related
      ENSGALP00010040477.1, ENSGALT00010066211.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      3992600..3999538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040692926.2 → XP_040548860.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3

      UniProtKB/TrEMBL
      A0A8V1A8H6, A0A8V1AB62
      Conserved Domains (1) summary
      cd00077
      Location:355 → 537
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    2. XM_040692925.2 → XP_040548859.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4

      UniProtKB/TrEMBL
      A0A8V1A3M2, A0A8V1A8H6
      Conserved Domains (1) summary
      cd00077
      Location:355 → 537
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    3. XM_040692924.2 → XP_040548858.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

    4. XM_040692923.2 → XP_040548857.2  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8H6
    Nucleotide Protein Strain
    Heading Accession and Version

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