U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MCU mitochondrial calcium uniporter [ Gallus gallus (chicken) ]

    Gene ID: 428942, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Symbol
    MCUprovided by CGNC
    Full Name
    mitochondrial calcium uniporterprovided by CGNC
    Primary source
    CGNC:3206
    See related
    Ensembl:ENSGALG00010021411
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CCDC109A
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MCU in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (11981445..12062178, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (12026671..12107400, complement)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene prolyl 4-hydroxylase subunit alpha 1 Neighboring gene nudix hydrolase 13 Neighboring gene phospholipase A2 group XIIB Neighboring gene oncoprotein induced transcript 3 Neighboring gene mitochondrial calcium uptake 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member B12

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Shanmughapriya S, et al. Sci Signal, 2015 Mar 3. PMID 25737585, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables uniporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium import into the mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitochondrial calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of uniplex complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    coiled-coil domain-containing protein 109A; calcium uniporter protein, mitochondrial
    Names
    coiled-coil domain containing 109A

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11981445..12062178 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015288227.4 → XP_015143713.1  calcium uniporter protein, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam04678
      Location:111 → 313
      MCU; Mitochondrial calcium uniporter

    2. XM_426497.8 → XP_426497.2  calcium uniporter protein, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A1D5P9H3, A0A8V0ZI27
      Related
      ENSGALP00010030986.1, ENSGALT00010051920.1
      Conserved Domains (1) summary
      pfam04678
      Location:111 → 313
      MCU; Mitochondrial calcium uniporter

    3. XM_046943142.1 → XP_046799098.1  calcium uniporter protein, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI27
      Related
      ENSGALP00010030962.1, ENSGALT00010051894.1

    4. XM_046943141.1 → XP_046799097.1  calcium uniporter protein, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZQG9

    5. XM_025151715.3 → XP_025007483.1  calcium uniporter protein, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI27
      Conserved Domains (1) summary
      pfam04678
      Location:73 → 275
      MCU; Mitochondrial calcium uniporter

    6. XM_040702672.2 → XP_040558606.1  calcium uniporter protein, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZQG9

    7. XM_040702673.2 → XP_040558607.1  calcium uniporter protein, mitochondrial isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZQG9
      Related
      ENSGALP00010030983.1, ENSGALT00010051915.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12026671..12107400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040674317.2 → XP_040530251.1  calcium uniporter protein, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam04678
      Location:111 → 313
      MCU; Mitochondrial calcium uniporter

    2. XM_040674319.2 → XP_040530253.1  calcium uniporter protein, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A1D5P9H3, A0A8V0ZI27
      Conserved Domains (1) summary
      pfam04678
      Location:111 → 313
      MCU; Mitochondrial calcium uniporter

    3. XM_046920626.1 → XP_046776582.1  calcium uniporter protein, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI27

    4. XM_046920625.1 → XP_046776581.1  calcium uniporter protein, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZQG9

    5. XM_040674320.2 → XP_040530254.1  calcium uniporter protein, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI27

    6. XM_040674316.2 → XP_040530250.1  calcium uniporter protein, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZQG9
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.