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    ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 [ Gallus gallus (chicken) ]

    Gene ID: 423712, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS14provided by CGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 14provided by CGNC
    Primary source
    CGNC:3306
    See related
    Ensembl:ENSGALG00010020285
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS14 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (12257876..12278451)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (12303763..12324400)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 20 Neighboring gene eukaryotic translation initiation factor 4E binding protein 2 Neighboring gene phosphatase domain containing, paladin 1 Neighboring gene steroidogenic acute regulatory protein, mitochondrial-like Neighboring gene microsomal triglyceride transfer protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      12257876..12278451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004942045.5 → XP_004942102.1  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDY6
      Related
      ENSGALP00010028926.1, ENSGALT00010048943.1
      Conserved Domains (5) summary
      smart00209
      Location:538 → 590
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 440
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:241 → 443
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:74 → 192
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:697 → 812
      ADAM_spacer1; ADAM-TS Spacer 1

    2. XM_003641474.6 → XP_003641522.2  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2

      Conserved Domains (5) summary
      smart00209
      Location:535 → 587
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 437
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:241 → 440
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:74 → 192
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:694 → 809
      ADAM_spacer1; ADAM-TS Spacer 1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12303763..12324400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040674750.2 → XP_040530684.1  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1

      Conserved Domains (3) summary
      smart00209
      Location:538 → 590
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 440
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:697 → 812
      ADAM_spacer1; ADAM-TS Spacer 1

    2. XM_040674751.2 → XP_040530685.1  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2

      Conserved Domains (3) summary
      smart00209
      Location:535 → 587
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:239 → 437
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:694 → 809
      ADAM_spacer1; ADAM-TS Spacer 1
    Nucleotide Protein
    Heading Accession and Version

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