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    CBFA2T3 CBFA2/RUNX1 translocation partner 3 [ Gallus gallus (chicken) ]

    Gene ID: 415846, updated on 3-Dec-2024

    Summary

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    Symbol
    CBFA2T3provided by CGNC
    Full Name
    CBFA2/RUNX1 translocation partner 3provided by CGNC
    Primary source
    CGNC:4681
    See related
    Ensembl:ENSGALG00010007930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    MTG16a; MTG16b
    Orthologs
    human mouse all
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    Genomic context

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    See CBFA2T3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18169888..18191832, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18517548..18539606, complement)

    Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex 2 like Neighboring gene poly(A) binding protein nuclear 1 like, cytoplasmic Neighboring gene acyl-CoA synthetase family member 3 Neighboring gene uncharacterized LOC124417138 Neighboring gene cadherin 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The expression and function of MTG/ETO family proteins during neurogenesis. Koyano-Nakagawa N, et al. Dev Biol, 2005 Feb 1. PMID 15649458
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein CBFA2T3
    Names
    core-binding factor, runt domain, alpha subunit 2; translocated to, 3
    myeloid translocation gene-related protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030580.2 → NP_001025751.2  protein CBFA2T3

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000248
      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2X1
      Related
      ENSGALP00010010476.1, ENSGALT00010018927.1
      Conserved Domains (3) summary
      smart00549
      Location:114 → 204
      TAFH; TAF homology
      COG2811
      Location:429 → 495
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam08788
      Location:325 → 391
      NHR2; NHR2 domain like

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18169888..18191832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025154190.3 → XP_025009958.2  protein CBFA2T3 isoform X2

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      Conserved Domains (3) summary
      PTZ00121
      Location:319 → 510
      PTZ00121; MAEBL; Provisional
      smart00549
      Location:140 → 230
      TAFH; TAF homology
      pfam08788
      Location:351 → 417
      NHR2; NHR2 domain like

    2. XM_025154189.3 → XP_025009957.2  protein CBFA2T3 isoform X1

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0XZH1
      Related
      ENSGALP00010010473.1, ENSGALT00010018923.1
      Conserved Domains (3) summary
      smart00549
      Location:140 → 230
      TAFH; TAF homology
      COG2811
      Location:455 → 521
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam08788
      Location:351 → 417
      NHR2; NHR2 domain like

    3. XM_025154193.3 → XP_025009961.2  protein CBFA2T3 isoform X4

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2W1
      Related
      ENSGALP00010010466.1, ENSGALT00010018916.1
      Conserved Domains (4) summary
      COG2811
      Location:402 → 468
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam08788
      Location:298 → 364
      NHR2; NHR2 domain like
      pfam01753
      Location:474 → 510
      zf-MYND; MYND finger
      pfam07531
      Location:87 → 175
      TAFH; NHR1 homology to TAF

    4. XM_025154191.3 → XP_025009959.2  protein CBFA2T3 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2V5
      Related
      ENSGALP00010010461.1, ENSGALT00010018911.1
      Conserved Domains (4) summary
      COG2811
      Location:428 → 494
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam08788
      Location:324 → 390
      NHR2; NHR2 domain like
      pfam01753
      Location:500 → 536
      zf-MYND; MYND finger
      pfam07531
      Location:113 → 201
      TAFH; NHR1 homology to TAF

    5. XM_025154192.3 → XP_025009960.2  protein CBFA2T3 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2V5
      Conserved Domains (4) summary
      COG2811
      Location:428 → 494
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam08788
      Location:324 → 390
      NHR2; NHR2 domain like
      pfam01753
      Location:500 → 536
      zf-MYND; MYND finger
      pfam07531
      Location:113 → 201
      TAFH; NHR1 homology to TAF

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18517548..18539606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046925607.1 → XP_046781563.1  protein CBFA2T3 isoform X2

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75

    2. XM_046925606.1 → XP_046781562.1  protein CBFA2T3 isoform X1

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75

    3. XM_046925609.1 → XP_046781565.1  protein CBFA2T3 isoform X4

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2W1

    4. XM_046925608.1 → XP_046781564.1  protein CBFA2T3 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2V5

    5. XM_046925611.1 → XP_046781567.1  protein CBFA2T3 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3B1, Q5IJ74, Q5IJ75
      UniProtKB/TrEMBL
      A0A8V0Y2V5
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F3B1.1 GenPept UniProtKB/Swiss-Prot:Q5F3B1

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