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    PRDM16 PR/SET domain 16 [ Gallus gallus (chicken) ]

    Gene ID: 419388, updated on 17-Aug-2024

    Summary

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    Symbol
    PRDM16provided by CGNC
    Full Name
    PR/SET domain 16provided by CGNC
    Primary source
    CGNC:719
    See related
    Ensembl:ENSGALG00010019648
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PRDM16 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (1029448..1428022, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (1061131..1459500, complement)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 6 Neighboring gene Rho guanine nucleotide exchange factor 16 Neighboring gene actin-85C-like Neighboring gene uncharacterized LOC419389 Neighboring gene uncharacterized LOC121107370 Neighboring gene uncharacterized LOC121107369 Neighboring gene actin related protein T2 Neighboring gene tetratricopeptide repeat domain 34 Neighboring gene membrane metallo-endopeptidase-like 1 Neighboring gene uncharacterized LOC124417344 Neighboring gene hes family bHLH transcription factor 5B Neighboring gene hes family bHLH transcription factor 5C Neighboring gene hes family bHLH transcription factor 5A Neighboring gene pantothenate kinase 4 Neighboring gene phospholipase C eta 2 Neighboring gene kainate binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel SNPs in the PRDM16 gene and their associations with performance traits in chickens. Han R, et al. Mol Biol Rep, 2012 Mar. PMID 21761141
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The GG genotype of c.1433G>A in PRDM16 favored chicken growth and fatness traits.
      Title: Novel SNPs in the PRDM16 gene and their associations with performance traits in chickens.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone H3K9 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PR domain zinc finger protein 16; histone-lysine N-methyltransferase PRDM16
    Names
    PR domain containing 16
    PR domain-containing 16-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1029448..1428022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025142614.3 → XP_024998382.1  histone-lysine N-methyltransferase PRDM16 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZBQ1
      Conserved Domains (5) summary
      sd00017
      Location:954 → 974
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:71 → 232
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:952 → 974
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:966 → 990
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:982 → 1037
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    2. XM_004947378.5 → XP_004947435.1  histone-lysine N-methyltransferase PRDM16 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZBQ1
      Conserved Domains (5) summary
      sd00017
      Location:955 → 975
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:71 → 232
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:953 → 975
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:967 → 991
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:983 → 1038
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    3. XM_040651288.2 → XP_040507222.1  histone-lysine N-methyltransferase PRDM16 isoform X4

      UniProtKB/TrEMBL
      A0A1D5PB87
      Conserved Domains (1) summary
      sd00017
      Location:726 → 746
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_417551.8 → XP_417551.3  histone-lysine N-methyltransferase PRDM16 isoform X3

      UniProtKB/TrEMBL
      A0A1D5PB87, A0A3Q3AHL1
      Related
      ENSGALP00010028089.1, ENSGALT00010047405.1
      Conserved Domains (5) summary
      sd00017
      Location:945 → 965
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:61 → 222
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:943 → 965
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:957 → 981
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:973 → 1028
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1061131..1459500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040689012.2 → XP_040544946.1  histone-lysine N-methyltransferase PRDM16 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZBQ1
      Conserved Domains (5) summary
      sd00017
      Location:954 → 974
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:71 → 232
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:952 → 974
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:966 → 990
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:982 → 1037
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    2. XM_040689010.2 → XP_040544944.1  histone-lysine N-methyltransferase PRDM16 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZBQ1
      Conserved Domains (5) summary
      sd00017
      Location:955 → 975
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:71 → 232
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:953 → 975
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:967 → 991
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:983 → 1038
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    3. XM_040689014.2 → XP_040544948.1  histone-lysine N-methyltransferase PRDM16 isoform X4

      UniProtKB/TrEMBL
      A0A1D5PB87
      Conserved Domains (1) summary
      sd00017
      Location:726 → 746
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_040689013.2 → XP_040544947.1  histone-lysine N-methyltransferase PRDM16 isoform X3

      UniProtKB/TrEMBL
      A0A1D5PB87, A0A3Q3AHL1
      Conserved Domains (5) summary
      sd00017
      Location:945 → 965
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd19213
      Location:61 → 222
      PR-SET_PRDM16; PR-SET domain found in PR domain zinc finger protein 16 (PRDM16) and similar proteins
      pfam00096
      Location:943 → 965
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:957 → 981
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:973 → 1028
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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