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    SHANK2 SH3 and multiple ankyrin repeat domains 2 [ Gallus gallus (chicken) ]

    Gene ID: 428858, updated on 3-Dec-2024

    Summary

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    Symbol
    SHANK2provided by CGNC
    Full Name
    SH3 and multiple ankyrin repeat domains 2provided by CGNC
    Primary source
    CGNC:5836
    See related
    Ensembl:ENSGALG00010024791
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SHANK2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (17479889..17823099, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (17439671..17783175, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain-containing protein 1-like Neighboring gene PTPRF interacting protein alpha 1 Neighboring gene cortactin Neighboring gene uncharacterized LOC121113263 Neighboring gene uncharacterized LOC121110953 Neighboring gene uncharacterized LOC121113265 Neighboring gene uncharacterized LOC121113264 Neighboring gene actin, beta-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ionotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables synaptic receptor adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH3 and multiple ankyrin repeat domains protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      17479889..17823099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701785.2 → XP_040557719.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    2. XM_040701784.2 → XP_040557718.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    3. XM_015286884.4 → XP_015142370.3  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZZW6
      Conserved Domains (6) summary
      cd09506
      Location:1804 → 1869
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:630 → 723
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:535 → 586
      SH3; Src Homology 3 domain superfamily

    4. XM_015286880.4 → XP_015142366.3  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    5. XM_040701782.2 → XP_040557716.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    6. XM_040701781.2 → XP_040557715.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    7. XM_040701780.2 → XP_040557714.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    8. XM_040701786.2 → XP_040557720.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    9. XM_040701787.2 → XP_040557721.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZZW6
      Related
      ENSGALP00010037281.1, ENSGALT00010060522.1
      Conserved Domains (6) summary
      cd09506
      Location:1804 → 1869
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:630 → 723
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:535 → 586
      SH3; Src Homology 3 domain superfamily

    10. XM_015286881.4 → XP_015142367.3  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Related
      ENSGALP00010037282.1, ENSGALT00010060523.1
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    11. XM_040701778.2 → XP_040557712.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    12. XM_046942393.1 → XP_046798349.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZZW6

    13. XM_046942392.1 → XP_046798348.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZZW6

    14. XM_046942394.1 → XP_046798350.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZUQ6

    15. XM_046942391.1 → XP_046798347.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZUQ6
      Related
      ENSGALP00010037279.1, ENSGALT00010060520.1

    16. XM_046942390.1 → XP_046798346.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V1A483

    17. XM_040701789.2 → XP_040557723.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X10

      Conserved Domains (4) summary
      cd09506
      Location:1396 → 1461
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd00992
      Location:242 → 335
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17036
      Location:147 → 198
      SH3; Src Homology 3 domain superfamily
      cl40703
      Location:937 → 1004
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)

    18. XM_015286889.4 → XP_015142375.3  SH3 and multiple ankyrin repeat domains protein 2 isoform X9

      Conserved Domains (4) summary
      cd09506
      Location:1416 → 1481
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd00992
      Location:242 → 335
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17036
      Location:147 → 198
      SH3; Src Homology 3 domain superfamily
      cl40703
      Location:957 → 1024
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      17439671..17783175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040673276.2 → XP_040529210.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    2. XM_040673275.2 → XP_040529209.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    3. XM_040673280.2 → XP_040529214.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZZW6
      Conserved Domains (6) summary
      cd09506
      Location:1804 → 1869
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:630 → 723
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:535 → 586
      SH3; Src Homology 3 domain superfamily

    4. XM_040673266.2 → XP_040529200.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    5. XM_040673273.2 → XP_040529207.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    6. XM_040673272.2 → XP_040529206.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    7. XM_040673271.2 → XP_040529205.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    8. XM_040673278.2 → XP_040529212.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1811 → 1876
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:157 → 375
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:637 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:229 → 260
      ANK; ANK repeat [structural motif]
      cd17176
      Location:54 → 141
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:542 → 593
      SH3; Src Homology 3 domain superfamily

    9. XM_040673279.2 → XP_040529213.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZZW6
      Conserved Domains (6) summary
      cd09506
      Location:1804 → 1869
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:630 → 723
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:535 → 586
      SH3; Src Homology 3 domain superfamily

    10. XM_040673267.2 → XP_040529201.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    11. XM_040673268.2 → XP_040529202.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1A483
      Conserved Domains (6) summary
      cd09506
      Location:1821 → 1886
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      PHA03095
      Location:167 → 385
      PHA03095; ankyrin-like protein; Provisional
      cd00992
      Location:647 → 740
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:239 → 270
      ANK; ANK repeat [structural motif]
      cd17176
      Location:64 → 151
      FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
      cl17036
      Location:552 → 603
      SH3; Src Homology 3 domain superfamily

    12. XM_046919248.1 → XP_046775204.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZZW6

    13. XM_046919247.1 → XP_046775203.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZZW6

    14. XM_046919249.1 → XP_046775205.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZUQ6

    15. XM_046919246.1 → XP_046775202.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZUQ6

    16. XM_046919245.1 → XP_046775201.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V1A483

    17. XM_040673287.2 → XP_040529221.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X10

      Conserved Domains (4) summary
      cd09506
      Location:1396 → 1461
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd00992
      Location:242 → 335
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17036
      Location:147 → 198
      SH3; Src Homology 3 domain superfamily
      cl40703
      Location:937 → 1004
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)

    18. XM_040673286.2 → XP_040529220.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X9

      Conserved Domains (4) summary
      cd09506
      Location:1416 → 1481
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd00992
      Location:242 → 335
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17036
      Location:147 → 198
      SH3; Src Homology 3 domain superfamily
      cl40703
      Location:957 → 1024
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
    Nucleotide Protein Strain
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