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    LINC00320 long intergenic non-protein coding RNA 320 [ Homo sapiens (human) ]

    Gene ID: 387486, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00320provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 320provided by HGNC
    Primary source
    HGNC:HGNC:19690
    See related
    Ensembl:ENSG00000224924 AllianceGenome:HGNC:19690
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRED14; C21orf131; NCRNA00320
    Expression
    Restricted expression toward brain (RPKM 6.9) See more
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    Genomic context

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    See LINC00320 in Genome Data Viewer
    Location:
    21q21.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (20742590..20803108, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (19104999..19165518, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (22114908..22175426, complement)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene RPS3A pseudogene 1 Neighboring gene MPRA-validated peak4373 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr21:21943094-21943647 Neighboring gene MPRA-validated peak4374 silencer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:21964409-21965608 Neighboring gene uncharacterized LOC124905064 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr21:22033338-22033876 Neighboring gene Sharpr-MPRA regulatory region 8374 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:22061254-22062453 Neighboring gene MPRA-validated peak4375 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:22162172-22162685 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:22162686-22163198 Neighboring gene MPRA-validated peak4376 silencer Neighboring gene peptidylprolyl isomerase A pseudogene 1 Neighboring gene uncharacterized LOC124905057

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA Linc00320 inhibits glioma cell proliferation through restraining Wnt/β-catenin signaling. Tian S, et al. Biochem Biophys Res Commun, 2019 Jan 8. PMID 30503496
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • FLJ37539, DKFZp686B23275

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024090.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate 3' exon, compared to variant 1.
      Source sequence(s)
      AK094858, AP000957, BC042856, BC064598, BX537735
      Related
      ENST00000437238.7

    2. NR_109786.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AK094858, AP000957, BC042856, BC047405, BC064598, BX537735
      Related
      ENST00000658703.1

    3. NR_109787.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate 5' exon and lacks multiple internal exons, compared to variant 1.
      Source sequence(s)
      AK094858, AP000957, BC042856, BC064598, BX537735
      Related
      ENST00000416768.6

    4. NR_109788.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate 5' exon and lacks multiple internal exons, compared to variant 1.
      Source sequence(s)
      AK094858, AP000957, BC042856, BC064598, BX537735
      Related
      ENST00000658084.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      20742590..20803108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      19104999..19165518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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