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    WSC4 Wsc4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856357, updated on 9-Dec-2024

    Summary

    Official Symbol
    WSC4
    Official Full Name
    Wsc4p
    Primary source
    SGD:S000001020
    Locus tag
    YHL028W
    See related
    AllianceGenome:SGD:S000001020; FungiDB:YHL028W; VEuPathDB:YHL028W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YFW1; YHC8
    Summary
    Enables protein transmembrane transporter activity. Involved in protein targeting to ER; protein targeting to membrane; and response to heat. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See WSC4 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (48763..50580)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Ecm29p Neighboring gene Oca5p Neighboring gene alkaline-responsive transcriptional regulator RIM101 Neighboring gene uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cell wall organization  
    involved_in protein targeting to ER PubMed 
    involved_in protein targeting to membrane PubMed 
    involved_in protein transmembrane transport  
    involved_in response to heat PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane PubMed 
    located_in membrane  

    General protein information

    Preferred Names
    Wsc4p
    NP_011835.1
    • Endoplasmic reticulum (ER) membrane protein; involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      48763..50580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179108.1NP_011835.1  TPA: Wsc4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011835.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKU0, P38739
      UniProtKB/TrEMBL
      B3LS91, B5VJQ1, C8ZA36, N1P2Q4
      Conserved Domains (1) summary
      smart00321
      Location:25109
      WSC; present in yeast cell wall integrity and stress response component proteins
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