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    PUF4 Puf4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852870, updated on 9-Dec-2024

    Summary

    Official Symbol
    PUF4
    Official Full Name
    Puf4p
    Primary source
    SGD:S000002982
    Locus tag
    YGL014W
    See related
    AllianceGenome:SGD:S000002982; FungiDB:YGL014W; VEuPathDB:YGL014W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YGL023
    Summary
    Enables mRNA binding activity. Involved in negative regulation of translation; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and protein localization. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See PUF4 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (466141..468807)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Kap122p Neighboring gene Bil2p Neighboring gene drug-responsive transcription factor PDR1 Neighboring gene delta(24(24(1)))-sterol reductase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding HDA PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Puf4p
    NP_011501.1
    • Member of the PUF protein family; PUF family is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      466141..468807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180879.1NP_011501.1  TPA: Puf4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011501.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUC3, P25339
      UniProtKB/TrEMBL
      G2WE79, N1P9T0
      Conserved Domains (1) summary
      COG5099
      Location:65888
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]