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    COX26 Cox26p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 3799970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    COX26
    Official Full Name
    Cox26p
    Primary source
    SGD:S000113555
    Locus tag
    YDR119W-A
    See related
    AllianceGenome:SGD:S000113555; FungiDB:YDR119W-A; VEuPathDB:YDR119W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrial inner membrane. Part of respiratory chain complex IV. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See COX26 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (691014..691214)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene anaphase promoting complex subunit 4 Neighboring gene Vba4p Neighboring gene tRNA (guanine26-N2)-dimethyltransferase Neighboring gene DNA polymerase epsilon noncatalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Strecker V, et al. Biochim Biophys Acta, 2016 Jul. PMID 27091403, Free PMC Article
    2. A three-way proteomics strategy allows differential analysis of yeast mitochondrial membrane protein complexes under anaerobic and aerobic conditions. Helbig AO, et al. Proteomics, 2009 Oct. PMID 19750512
    3. Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance. Berndtsson J, et al. EMBO Rep, 2020 Dec 3. PMID 33016568, Free PMC Article
    4. Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome c Oxidase Complex. Garlich J, et al. J Biol Chem, 2017 Mar 31. PMID 28167530, Free PMC Article
    5. Cox26 is a novel stoichiometric subunit of the yeast cytochrome c oxidase. Levchenko M, et al. Biochim Biophys Acta, 2016 Jul. PMID 27083394

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex IV IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cox26p
    NP_001032575.1
    • Subunit of cytochrome C oxidase complex; stabilizes or regulates formation of respiratory chain supercomplexes composed of Complex III (ubiquinol-cytochrome c reductase) and Complex IV (cytochrome c oxidase)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      691014..691214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184681.1 → NP_001032575.1  TPA: Cox26p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_001032575.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSA5, Q2V2P9
      UniProtKB/TrEMBL
      A6ZY81, B3LGF7, C7GIM7, G2WAM1, N1P6C3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2V2P9.1

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