U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    STF1 ATPase-binding protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851426, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    STF1
    Official Full Name
    ATPase-binding protein
    Primary source
    SGD:S000007232
    Locus tag
    YDL130W-A
    See related
    AllianceGenome:SGD:S000007232; FungiDB:YDL130W-A; VEuPathDB:YDL130W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AIS2
    Summary
    Enables ATPase binding activity. Involved in negative regulation of ATP-dependent activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See STF1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (229171..229431)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene cullin CDC53 Neighboring gene homocitrate synthase LYS21 Neighboring gene ribosomal protein P1B Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular cloning and expression of a gene for a factor which stabilizes formation of inhibitor-mitochondrial ATPase complex from Saccharomyces cerevisiae. Akashi A, et al. J Biochem, 1988 Oct. PMID 2907329
    2. Simultaneous bindings of ATPase inhibitor and 9K protein to F1F0-ATPase in the presence of 15K protein in yeast mitochondria. Hashimoto T, et al. J Biochem, 1990 Jul. PMID 2172220
    3. Investigation of the role and mechanism of IF1 and STF1 proteins, twin inhibitory peptides which interact with the yeast mitochondrial ATP synthase. Venard R, et al. Biochemistry, 2003 Jun 24. PMID 12809520
    4. Homologous and heterologous inhibitory effects of ATPase inhibitor proteins on F-ATPases. Cabezon E, et al. J Biol Chem, 2002 Nov 1. PMID 12186878
    5. A stabilizing factor of yeast mitochondrial F1F0-ATPase-inhibitor complex: common amino acid sequence with yeast ATPase inhibitor and E. coli epsilon and bovine delta subunits. Matsubara H, et al. J Biochem, 1983 Jul. PMID 6194151

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATPase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATPase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of ATP-dependent activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ATPase-binding protein
    NP_010152.1
    • Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein; protein abundance increases in response to DNA replication stress; STF1 has a paralog, INH1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      229171..229431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184325.1 → NP_010152.1  TPA: ATPase-binding protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRL9, P01098
      UniProtKB/TrEMBL
      A6ZXJ8, B3LH21, C7GJI5, G2WC31, N1PA87
      Conserved Domains (1) summary
      pfam04568
      Location:24 → 86
      IATP; Mitochondrial ATPase inhibitor, IATP
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P01098.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools