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    SOG2 Sog2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854535, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SOG2
    Official Full Name
    Sog2p
    Primary source
    SGD:S000005880
    Locus tag
    YOR353C
    See related
    AllianceGenome:SGD:S000005880; FungiDB:YOR353C; VEuPathDB:YOR353C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in budding cell apical bud growth; septum digestion after cytokinesis; and signal transduction. Located in cellular bud; incipient cellular bud site; and mating projection tip. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SOG2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (998453..1000828, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase MEK1 Neighboring gene TFIIH complex subunit TFB6 Neighboring gene Msc6p Neighboring gene Gds1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in the C-terminus of the conserved NDR kinase, Cbk1p of Saccharomyces cerevisiae, make the protein independent of upstream activators. Panozzo C, et al. Mol Genet Genomics, 2010 Feb. PMID 19967545
    2. RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Nelson B, et al. Mol Biol Cell, 2003 Sep. PMID 12972564, Free PMC Article
    3. A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity. Kurischko C, et al. Genetics, 2005 Oct. PMID 15972461, Free PMC Article
    4. Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages. Janschitz M, et al. Cell Commun Signal, 2019 Jun 17. PMID 31208443, Free PMC Article
    5. Systematic analysis of bypass suppression of essential genes. van Leeuwen J, et al. Mol Syst Biol, 2020 Sep. PMID 32939983, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in budding cell apical bud growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in septum digestion after cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cellular bud IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in incipient cellular bud site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mating projection tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Sog2p
    NP_014998.3
    • Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      998453..1000828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183773.3 → NP_014998.3  TPA: Sog2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014998.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W348, Q08817
      UniProtKB/TrEMBL
      G2WNL4, N1NXI7
      Conserved Domains (3) summary
      COG4886
      Location:18 → 266
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:68 → 90
      LRR_1; leucine-rich repeat [structural motif]
      pfam10428
      Location:299 → 781
      SOG2; RAM signalling pathway protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08817.1

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