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    Zfp267 zinc finger protein 267 [ Mus musculus (house mouse) ]

    Gene ID: 241944, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp267provided by MGI
    Official Full Name
    zinc finger protein 267provided by MGI
    Primary source
    MGI:MGI:1098769
    See related
    Ensembl:ENSMUSG00000033883 AllianceGenome:MGI:1098769
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D3Ertd254e
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF267 (zinc finger protein 267). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 1.9), CNS E14 (RPKM 1.8) and 26 other tissues See more
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    Genomic context

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    See Zfp267 in Genome Data Viewer
    Location:
    3 B; 3 17.41 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (36205233..36224491)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (36151080..36170341)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene acyl-Coenzyme A dehydrogenase family, member 9 Neighboring gene STARR-seq mESC enhancer starr_07416 Neighboring gene STARR-seq mESC enhancer starr_07417 Neighboring gene predicted gene, 54173 Neighboring gene STARR-positive B cell enhancer ABC_E10177 Neighboring gene pyroglutamylated RFamide peptide receptor Neighboring gene POU domain, class 5, transcription factor 1, related sequence 11 Neighboring gene STARR-seq mESC enhancer starr_07420 Neighboring gene STARR-seq mESC enhancer starr_07421 Neighboring gene predicted gene, 42208

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Candidate genes and their regulatory elements: alcohol preference and tolerance. Saba L, et al. Mamm Genome, 2006 Jun. PMID 16783646
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC241944

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101478.2 → NP_001094948.1  uncharacterized protein LOC241944

      See identical proteins and their annotated locations for NP_001094948.1

      Status: VALIDATED

      Source sequence(s)
      AC158934
      Consensus CDS
      CCDS79898.1
      UniProtKB/TrEMBL
      A0A0G2JEM5
      Related
      ENSMUSP00000142829.2, ENSMUST00000197653.5
      Conserved Domains (6) summary
      smart00349
      Location:4 → 64
      KRAB; krueppel associated box
      COG5048
      Location:479 → 633
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:247 → 470
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:482 → 502
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:662 → 687
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      36205233..36224491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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