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    Immp1l IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 66541, updated on 27-Nov-2024

    Summary

    Official Symbol
    Immp1lprovided by MGI
    Official Full Name
    IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1913791
    See related
    Ensembl:ENSMUSG00000042670 AllianceGenome:MGI:1913791
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500034J20Rik; 2610528O17Rik
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Located in mitochondrion. Orthologous to human IMMP1L (inner mitochondrial membrane peptidase subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 17.3), bladder adult (RPKM 15.8) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Immp1l in Genome Data Viewer
    Location:
    2 E3; 2 55.43 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (105735013..105795904)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (105904638..105965558)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene paired box 6 opposite strand 1 Neighboring gene Pax6 upstream regulatory region Neighboring gene STARR-seq mESC enhancer starr_05314 Neighboring gene enhancer in intron 4 of Pax6 Neighboring gene enhancer region in intron 7 of Pax6 Neighboring gene Pax6 upstream antisense RNA Neighboring gene STARR-seq mESC enhancer starr_05317 Neighboring gene paired box 6 Neighboring gene elongator acetyltransferase complex subunit 4 Neighboring gene RB enhancer downstream of Pax6 Neighboring gene Pax6 downstream regulatory region Neighboring gene STARR-seq mESC enhancer starr_05318 Neighboring gene STARR-seq mESC enhancer starr_05319 Neighboring gene STARR-positive B cell enhancer ABC_E639 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:105843384-105843567 Neighboring gene DnaJ heat shock protein family (Hsp40) member C24 Neighboring gene doublecortin domain containing 5 Neighboring gene 60S ribosomal protein L39 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Clone Names

    • MGC101970

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein processing involved in protein targeting to mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of mitochondrial inner membrane peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial inner membrane protease subunit 1
    Names
    IMP1-like protein
    NP_082536.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028260.3NP_082536.1  mitochondrial inner membrane protease subunit 1

      See identical proteins and their annotated locations for NP_082536.1

      Status: VALIDATED

      Source sequence(s)
      AL590380
      Consensus CDS
      CCDS38192.1
      UniProtKB/Swiss-Prot
      Q3THN4, Q9CQU8
      Related
      ENSMUSP00000049044.6, ENSMUST00000037499.6
      Conserved Domains (1) summary
      TIGR02227
      Location:29149
      sigpep_I_bact; signal peptidase I, bacterial type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      105735013..105795904
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)