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    Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 [ Mus musculus (house mouse) ]

    Gene ID: 631304, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cyp4f40provided by MGI
    Official Full Name
    cytochrome P450, family 4, subfamily f, polypeptide 40provided by MGI
    Primary source
    MGI:MGI:3645508
    See related
    Ensembl:ENSMUSG00000090700 AllianceGenome:MGI:3645508
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG631304
    Summary
    Predicted to enable fatty acid binding activity and monooxygenase activity. Predicted to be involved in icosanoid metabolic process; menaquinone catabolic process; and phylloquinone catabolic process. Orthologous to human CYP4F11 (cytochrome P450 family 4 subfamily F member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in large intestine adult (RPKM 63.3), colon adult (RPKM 23.3) and 2 other tissues See more
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    Genomic context

    See Cyp4f40 in Genome Data Viewer
    Location:
    17 B1; 17 17.71 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (32877860..32895893)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32658886..32676919)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42390 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 37 Neighboring gene STARR-seq mESC enhancer starr_42391 Neighboring gene cytochrome P450, family 4, subfamily f, member 38, pseudogene Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 15 Neighboring gene predicted gene, 53996

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General protein information

    Preferred Names
    cytochrome P450, family 4, subfamily f, polypeptide 40

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101588.2NP_001095058.1  cytochrome P450, family 4, subfamily f, polypeptide 40

      See identical proteins and their annotated locations for NP_001095058.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      CT033759
      Consensus CDS
      CCDS50060.1
      UniProtKB/TrEMBL
      B2RY43, G3UW81
      Related
      ENSMUSP00000129536.2, ENSMUST00000165061.2
      Conserved Domains (1) summary
      pfam00067
      Location:52515
      p450; Cytochrome P450
    2. NM_001368735.1NP_001355664.1  cytochrome P450, family 4, subfamily f, polypeptide 40

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      CT033759
      Consensus CDS
      CCDS50060.1
      UniProtKB/TrEMBL
      B2RY43, G3UW81
      Related
      ENSMUSP00000157311.2, ENSMUST00000235086.2
      Conserved Domains (1) summary
      pfam00067
      Location:52515
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      32877860..32895893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524759.1XP_006524822.1  cytochrome P450, family 4, subfamily f, polypeptide 40 isoform X2

      See identical proteins and their annotated locations for XP_006524822.1

      UniProtKB/TrEMBL
      B2RY43, G3UW81
      Conserved Domains (1) summary
      pfam00067
      Location:52515
      p450; Cytochrome P450
    2. XM_006524757.2XP_006524820.1  cytochrome P450, family 4, subfamily f, polypeptide 40 isoform X1

      UniProtKB/TrEMBL
      B2RY43
      Conserved Domains (1) summary
      pfam00067
      Location:79542
      p450; Cytochrome P450