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    Calhm1 calcium homeostasis modulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 546729, updated on 9-Dec-2024

    Summary

    Official Symbol
    Calhm1provided by MGI
    Official Full Name
    calcium homeostasis modulator 1provided by MGI
    Primary source
    MGI:MGI:3643383
    See related
    Ensembl:ENSMUSG00000079258 AllianceGenome:MGI:3643383
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG546729
    Summary
    Enables voltage-gated calcium channel activity. Involved in ATP export; protein heterooligomerization; and sensory perception of taste. Located in basolateral plasma membrane and plasma membrane raft. Is expressed in forebrain; gut; and male reproductive gland or organ. Orthologous to human CALHM1 (calcium homeostasis modulator 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Calhm1 in Genome Data Viewer
    Location:
    19 C3; 19 39.36 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (47129474..47132613, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (47141035..47144174, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11038 Neighboring gene programmed cell death 11 Neighboring gene STARR-positive B cell enhancer ABC_E11039 Neighboring gene STARR-positive B cell enhancer ABC_E8754 Neighboring gene STARR-seq mESC enhancer starr_46339 Neighboring gene calcium homeostasis modulator family member 2 Neighboring gene STARR-seq mESC enhancer starr_46340 Neighboring gene calcium homeostasis modulator 3 Neighboring gene STARR-positive B cell enhancer ABC_E11679 Neighboring gene H1.11 linker histone, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in ATP export PubMed 
    involved_in ATP export  
    involved_in ATP transport PubMed 
    involved_in calcium ion transmembrane transport  
    involved_in monoatomic cation transport  
    involved_in monoatomic cation transport  
    involved_in protein heterooligomerization PubMed 
    involved_in protein homooligomerization  
    involved_in protein homooligomerization  
    involved_in regulation of monoatomic ion transmembrane transport  
    involved_in regulation of monoatomic ion transmembrane transport  
    involved_in sensory perception of bitter taste PubMed 
    involved_in sensory perception of sweet taste PubMed 
    involved_in sensory perception of taste PubMed 
    involved_in sensory perception of umami taste PubMed 
    Component Evidence Code Pubs
    located_in basolateral plasma membrane PubMed 
    located_in endoplasmic reticulum membrane  
    is_active_in plasma membrane  
    located_in plasma membrane PubMed 
    located_in plasma membrane  
    located_in plasma membrane  
    located_in plasma membrane  
    located_in plasma membrane raft PubMed 

    General protein information

    Preferred Names
    calcium homeostasis modulator protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081271.1NP_001074740.1  calcium homeostasis modulator protein 1

      See identical proteins and their annotated locations for NP_001074740.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124724
      Consensus CDS
      CCDS38015.1
      UniProtKB/Swiss-Prot
      D3Z291
      UniProtKB/TrEMBL
      A0A1Y1C8H8
      Related
      ENSMUSP00000107444.2, ENSMUST00000111813.3
      Conserved Domains (1) summary
      pfam14798
      Location:1254
      Ca_hom_mod; Calcium homeostasis modulator

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      47129474..47132613 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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