Dgat2l6 diacylglycerol O-acyltransferase 2-like 6 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dgat2l6provided by MGI
Official Full Name: diacylglycerol O-acyltransferase 2-like 6provided by MGI
Primary source: MGI:MGI:3045268
See related: Ensembl:ENSMUSG00000067597 AllianceGenome:MGI:3045268
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 9930021F22Rik
Summary: Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in monoacylglycerol biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in Harderian gland; ileum; jejunum; and skin. Orthologous to human DGAT2L6 (diacylglycerol O-acyltransferase 2 like 6). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
Orthologs: human all
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Genomic context

Location:: X C3; X 43.72 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (99568444..99589714)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (100524838..100546108)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables diacylglycerol O-acyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in lipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoacylglycerol biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in monoacylglycerol biosynthetic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: diacylglycerol O-acyltransferase 2-like protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114084.1 → NP_001107556.1 diacylglycerol O-acyltransferase 2-like protein 6

See identical proteins and their annotated locations for NP_001107556.1

Status: VALIDATED

Source sequence(s)

AL671299

Consensus CDS

CCDS53147.1

UniProtKB/Swiss-Prot

A2ADU8

Related

ENSMUSP00000036845.9, ENSMUST00000037541.9

Conserved Domains (1) summary

cl17185
Location:38 → 336

LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis