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    PFS1 Pfs1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PFS1
    Official Full Name
    Pfs1p
    Primary source
    SGD:S000001228
    Locus tag
    YHR185C
    See related
    AllianceGenome:SGD:S000001228; FungiDB:YHR185C; VEuPathDB:YHR185C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ADY1
    Summary
    Involved in ascospore wall assembly. Predicted to be located in cytoplasm; nucleus; and spindle pole body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PFS1 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (474627..475340, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene phosphogluconate dehydrogenase (decarboxylating) GND1 Neighboring gene Ssp1p Neighboring gene tRNA-Val Neighboring gene ubiquitin-binding TORC1 subunit KOG1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae. Deng C, et al. Mol Biol Cell, 2001 Sep. PMID 11553705, Free PMC Article
    2. Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast. Grabowska E, et al. Mol Microbiol, 2014 May. PMID 24628792
    3. Acetate regulation of spore formation is under the control of the Ras/cyclic AMP/protein kinase A pathway and carbon dioxide in Saccharomyces cerevisiae. Jungbluth M, et al. Eukaryot Cell, 2012 Aug. PMID 22660623, Free PMC Article
    4. Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Petronczki M, et al. Cell, 2006 Sep 22. PMID 16990132
    5. Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity. Dheur S, et al. J Biol Chem, 2005 Jul 1. PMID 15894541

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pfs1p
    NP_012055.3
    • Sporulation protein required for prospore membrane formation; required for prospore membrane formation at selected spindle poles; ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      474627..475340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179316.3 → NP_012055.3  TPA: Pfs1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012055.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLD3, P38872
      UniProtKB/TrEMBL
      A6ZT91, B3LSU6, B5VKB3, C7GRK7, C8Z9Y4, N1P303
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38872.1

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