U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    IES6 Ies6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856667, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    IES6
    Official Full Name
    Ies6p
    Primary source
    SGD:S000000770
    Locus tag
    YEL044W
    See related
    AllianceGenome:SGD:S000000770; FungiDB:YEL044W; VEuPathDB:YEL044W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in chromatin remodeling. Located in nucleus. Part of Ino80 complex. Orthologous to human INO80C (INO80 complex subunit C). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IES6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (69757..70257)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene fumarate reductase Neighboring gene threonine aldolase GLY1 Neighboring gene Gta1p Neighboring gene guanosine diphosphatase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Yu EY, et al. Mol Cell Biol, 2007 Aug. PMID 17562861, Free PMC Article
    2. The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Chambers AL, et al. Genes Dev, 2012 Dec 1. PMID 23207916, Free PMC Article
    3. The INO80 chromatin remodeler sustains metabolic stability by promoting TOR signaling and regulating histone acetylation. Beckwith SL, et al. PLoS Genet, 2018 Feb. PMID 29462149, Free PMC Article
    4. The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. Sing TL, et al. J Cell Biol, 2018 Jul 2. PMID 29875260, Free PMC Article
    5. Cycloheximide Inhibits Actin Cytoskeletal Dynamics by Suppressing Signaling via RhoA. Darvishi E, et al. J Cell Biochem, 2016 Dec. PMID 27192630

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Ino80 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Ino80 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Ies6p
    NP_010870.1
    • Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      69757..70257
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178859.1 → NP_010870.1  TPA: Ies6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010870.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLK5, P32617, Q6Q5Q5
      UniProtKB/TrEMBL
      A6ZQQ6, B3LRX2, C7GKE7, C8Z6V0, G2WCI9, N1P592
      Conserved Domains (1) summary
      cl02154
      Location:44 → 166
      YL1_C; YL1 nuclear protein C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32617.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools