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    SBE2 Sbe2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851953, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SBE2
    Official Full Name
    Sbe2p
    Primary source
    SGD:S000002759
    Locus tag
    YDR351W
    See related
    AllianceGenome:SGD:S000002759; FungiDB:YDR351W; VEuPathDB:YDR351W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in fungal-type cell wall organization. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SBE2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1178666..1181260)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA-Met Neighboring gene Atp22p Neighboring gene Ypq2p Neighboring gene thioredoxin-disulfide reductase TRR1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exploring whole-genome duplicate gene retention with complex genetic interaction analysis. Kuzmin E, et al. Science, 2020 Jun 26. PMID 32586993, Free PMC Article
    2. Identification of the bud emergence gene BEM4 and its interactions with rho-type GTPases in Saccharomyces cerevisiae. Mack D, et al. Mol Cell Biol, 1996 Aug. PMID 8754839, Free PMC Article
    3. Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation. Santos B, et al. Mol Biol Cell, 2000 Feb. PMID 10679005, Free PMC Article
    4. Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase. Wood CS, et al. Mol Biol Cell, 2012 Jul. PMID 22553352, Free PMC Article
    5. Structure-function analysis of Knr4/Smi1, a newly member of intrinsically disordered proteins family, indispensable in the absence of a functional PKC1-SLT2 pathway in Saccharomyces cerevisiae. Durand F, et al. Yeast, 2008 Aug. PMID 18668512

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sbe2p
    NP_010638.3
    • Protein required for bud growth; involved in transport of cell wall components from the Golgi to the cell surface; SBE2 has a paralog, SBE22, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1178666..1181260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180659.3 → NP_010638.3  TPA: Sbe2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010638.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZYV1, D6VSY1, P42223
      UniProtKB/TrEMBL
      B3LFV0, N1P5C0
      Conserved Domains (1) summary
      pfam17076
      Location:79 → 862
      SBE2; cell-wall formation
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42223.2

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