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    SPO21 Spo21p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854062, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SPO21
    Official Full Name
    Spo21p
    Primary source
    SGD:S000005451
    Locus tag
    YOL091W
    See related
    AllianceGenome:SGD:S000005451; FungiDB:YOL091W; VEuPathDB:YOL091W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MPC70
    Summary
    Enables structural molecule activity. Involved in ascospore-type prospore membrane formation. Located in meiotic spindle pole body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SPO21 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (145334..147163)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene tRNA (guanine(9)-N(1))-methyltransferase Neighboring gene cationic amino acid transporter Neighboring gene mismatch repair ATPase MSH2 Neighboring gene Hal9p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservative duplication of spindle poles during meiosis in Saccharomyces cerevisiae. Wesp A, et al. J Bacteriol, 2001 Apr. PMID 11244080, Free PMC Article
    2. SPO21 is required for meiosis-specific modification of the spindle pole body in yeast. Bajgier BK, et al. Mol Biol Cell, 2001 Jun. PMID 11408572, Free PMC Article
    3. Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system. Taxis C, et al. J Cell Biol, 2005 Nov 21. PMID 16286509, Free PMC Article
    4. Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast. King GA, et al. Elife, 2019 Aug 9. PMID 31397671, Free PMC Article
    5. Membrane assembly modulates the stability of the meiotic spindle-pole body. Mathieson EM, et al. J Cell Sci, 2010 Jul 15. PMID 20592185, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural molecule activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural molecule activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore-type prospore membrane formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ascospore-type prospore membrane formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole body HDA PubMed 

    General protein information

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    Preferred Names
    Spo21p
    NP_014550.1
    • Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation; SPO21 has a paralog, YSW1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      145334..147163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183345.1 → NP_014550.1  TPA: Spo21p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014550.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1X7, Q12411
      UniProtKB/TrEMBL
      G2WME4, N1NWC2
      Conserved Domains (1) summary
      COG1196
      Location:283 → 482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12411.1

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