Rnf227 ring finger protein 227 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rnf227provided by MGI
Official Full Name: ring finger protein 227provided by MGI
Primary source: MGI:MGI:1915359
See related: Ensembl:ENSMUSG00000043419 AllianceGenome:MGI:1915359
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: RNF21; Chd3os; MNCb-2875; 2310043C11Rik; A030009H04Rik
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in brain and spinal cord. Orthologous to human RNF227 (ring finger protein 227). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in CNS E18 (RPKM 38.4), frontal lobe adult (RPKM 30.6) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 B3; 11 42.52 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (69231282..69233467)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (69340796..69342641)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: RING finger protein 227

Names: Chd3 opposite strand transcript; chromodomain helicase DNA binding protein 3, opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001413473.1 → NP_001400402.1 RING finger protein 227

Status: VALIDATED

Source sequence(s)

AL645527

UniProtKB/Swiss-Prot

A0A140LI80, Q9DCB3, Q9JJ82

UniProtKB/TrEMBL

F1SW11

Related

ENSMUSP00000146712.2, ENSMUST00000129321.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

69231282..69233467

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_020591.1: Suppressed sequence

Description

NM_020591.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.