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    Tmem121b transmembrane protein 121B [ Mus musculus (house mouse) ]

    Gene ID: 94047, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem121bprovided by MGI
    Official Full Name
    transmembrane protein 121Bprovided by MGI
    Primary source
    MGI:MGI:2136977
    See related
    Ensembl:ENSMUSG00000094626 AllianceGenome:MGI:2136977
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cecr6
    Summary
    Orthologous to human TMEM121B (transmembrane protein 121B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human all
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    Genomic context

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    See Tmem121b in Genome Data Viewer
    Location:
    6 F1; 6 56.95 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (120465900..120470907, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (120488939..120493946, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lysine demethylase 5A Neighboring gene predicted gene, 24592 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120416743-120416991 Neighboring gene STARR-positive B cell enhancer ABC_E685 Neighboring gene STARR-positive B cell enhancer ABC_E10406 Neighboring gene interleukin 17 receptor A Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120479310-120479463 Neighboring gene haloacid dehalogenase like hydrolase domain containing 5 Neighboring gene RIKEN cDNA 1700072O05 gene Neighboring gene nonconserved acetylation island sequence M73 enhancer

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple features contribute to efficient constitutive splicing of an unusually large exon. Bruce SR, et al. Nucleic Acids Res, 2001 Jun 1. PMID 11376148, Free PMC Article
    2. Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. Footz TK, et al. Genome Res, 2001 Jun. PMID 11381032, Free PMC Article
    3. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
    4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
    5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    transmembrane protein 121B
    Names
    cat eye syndrome chromosome region, candidate 6 homolog
    cat eye syndrome critical region protein 6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033567.2 → NP_291045.1  transmembrane protein 121B

      See identical proteins and their annotated locations for NP_291045.1

      Status: VALIDATED

      Source sequence(s)
      AC078896
      Consensus CDS
      CCDS57446.1
      UniProtKB/Swiss-Prot
      Q99MX7
      UniProtKB/TrEMBL
      B2RQD1
      Related
      ENSMUSP00000135924.2, ENSMUST00000178687.2
      Conserved Domains (1) summary
      pfam14997
      Location:308 → 511
      CECR6_TMEM121; CECR6/TMEM121 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      120465900..120470907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99MX7.1 GenPept UniProtKB/Swiss-Prot:Q99MX7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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