Slc22a15 solute carrier family 22 (organic anion/cation transporter), member 15 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slc22a15provided by MGI
Official Full Name: solute carrier family 22 (organic anion/cation transporter), member 15provided by MGI
Primary source: MGI:MGI:3607704
See related: Ensembl:ENSMUSG00000033147 AllianceGenome:MGI:3607704
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930477M19; 2610034P21Rik; A530052I06Rik
Summary: Enables amino-acid betaine transmembrane transporter activity. Predicted to be involved in several processes, including amino acid transport; amino-acid betaine transport; and monoatomic ion transport. Predicted to be located in plasma membrane. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and urinary system. Orthologous to human SLC22A15 (solute carrier family 22 member 15). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in testis adult (RPKM 8.5), colon adult (RPKM 2.3) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 F2.2; 3 44.3 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (101763084..101831769, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (101854443..101928220, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:234785

NoName (e-PCR)
- UniSTS:487745

Slc22a15 (e-PCR), detects polymorphism
- UniSTS:527542

BB219042 (e-PCR)
- UniSTS:185555

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables amino-acid betaine transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino-acid betaine transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in amino acid transport	IEA Inferred from Electronic Annotation more info
involved_in amino-acid betaine transport	IEA Inferred from Electronic Annotation more info
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: solute carrier family 22 member 15

Names: solute carrier family 22 (organic cation transporter), member 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039371.2 → NP_001034460.2 solute carrier family 22 member 15

See identical proteins and their annotated locations for NP_001034460.2

Status: VALIDATED

Source sequence(s)

AC165165

Consensus CDS

CCDS51022.1

UniProtKB/Swiss-Prot

A7MCW2, F8WJ00, Q504N2, Q8CDR3

Related

ENSMUSP00000102541.3, ENSMUST00000106928.10

Conserved Domains (1) summary

cd06174
Location:121 → 469

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000069.7 Reference GRCm39 C57BL/6J

Range

101763084..101831769 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001039369.1: Suppressed sequence

Description

NM_001039369.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
NM_001039370.1: Suppressed sequence

Description

NM_001039370.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
NM_177729.2: Suppressed sequence

Description

NM_177729.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.