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    Ebpl emopamil binding protein-like [ Mus musculus (house mouse) ]

    Gene ID: 68177, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ebplprovided by MGI
    Official Full Name
    emopamil binding protein-likeprovided by MGI
    Primary source
    MGI:MGI:1915427
    See related
    Ensembl:ENSMUSG00000021928 AllianceGenome:MGI:1915427
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EBRP; 5730442K12Rik
    Summary
    Predicted to enable cholestenol delta-isomerase activity. Predicted to be involved in sterol metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in central nervous system; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human EBPL (EBP like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver adult (RPKM 31.5), bladder adult (RPKM 12.5) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Ebpl in Genome Data Viewer
    Location:
    14 D1; 14 32.72 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61577212..61597894, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61339763..61360445, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 11 Neighboring gene predicted gene 5461 Neighboring gene predicted gene, 25716 Neighboring gene STARR-positive B cell enhancer ABC_E8563 Neighboring gene karyopherin subunit alpha 3 Neighboring gene STARR-positive B cell enhancer ABC_E1898 Neighboring gene ribosomal protein S12, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cholestenol delta-isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in sterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    emopamil-binding protein-like
    Names
    emopamil binding related protein, delta8-delta7 sterol isomerase related protein
    emopamil-binding-related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026598.3NP_080874.2  emopamil-binding protein-like

      See identical proteins and their annotated locations for NP_080874.2

      Status: VALIDATED

      Source sequence(s)
      AC154435, AK019963, BY349880
      Consensus CDS
      CCDS27183.1
      UniProtKB/Swiss-Prot
      Q3TQR1, Q9CRQ2, Q9CY81, Q9D0P0
      Related
      ENSMUSP00000022494.9, ENSMUST00000022494.10
      Conserved Domains (1) summary
      pfam05241
      Location:24193
      EBP; Emopamil binding protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      61577212..61597894 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)