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    Rhbdl1 rhomboid like 1 [ Mus musculus (house mouse) ]

    Gene ID: 214951, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rhbdl1provided by MGI
    Official Full Name
    rhomboid like 1provided by MGI
    Primary source
    MGI:MGI:2384891
    See related
    Ensembl:ENSMUSG00000025735 AllianceGenome:MGI:2384891
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rhbdl
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is expressed in brain; male reproductive gland or organ; and spinal cord. Orthologous to human RHBDL1 (rhomboid like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 54.9), genital fat pad adult (RPKM 37.1) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Rhbdl1 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.93 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26053439..26056101, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25834465..25837127, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7500 Neighboring gene WD repeat domain 24 Neighboring gene jumonji domain containing 8 Neighboring gene STARR-positive B cell enhancer ABC_E3192 Neighboring gene microRNA 3082 Neighboring gene STIP1 homology and U-Box containing protein 1 Neighboring gene ras homolog family member T2 Neighboring gene WD repeat domain 90

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Potential readthrough

    Included gene: Rhot2

    Clone Names

    • MGC28800

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    rhomboid-related protein 1
    Names
    RRP
    rhomboid, veinlet-like 1
    rhomboid-like protein 1
    NP_659065.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144816.1NP_659065.1  rhomboid-related protein 1

      See identical proteins and their annotated locations for NP_659065.1

      Status: PROVISIONAL

      Source sequence(s)
      BC021549
      Consensus CDS
      CCDS28534.1
      UniProtKB/Swiss-Prot
      Q8VC82
      UniProtKB/TrEMBL
      Q3USF1, V9GX92
      Related
      ENSMUSP00000026831.7, ENSMUST00000026831.14
      Conserved Domains (1) summary
      pfam01694
      Location:174328
      Rhomboid; Rhomboid family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26053439..26056101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)