U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cc2d2b coiled-coil and C2 domain containing 2B [ Mus musculus (house mouse) ]

    Gene ID: 668310, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Cc2d2bprovided by MGI
    Official Full Name
    coiled-coil and C2 domain containing 2Bprovided by MGI
    Primary source
    MGI:MGI:3645359
    See related
    Ensembl:ENSMUSG00000108929 AllianceGenome:MGI:3645359
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm338; EG668310
    Summary
    Predicted to be involved in non-motile cilium assembly and protein localization to ciliary transition zone. Predicted to be active in ciliary transition zone. Orthologous to human CC2D2B (coiled-coil and C2 domain containing 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 4.6) and liver E14 (RPKM 0.2) See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Cc2d2b in Genome Data Viewer
    Location:
    19 C3; 19 34.26 cM
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (40737197..40818227)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (40748753..40829778)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ectonucleoside triphosphate diphosphohydrolase 1 Neighboring gene predicted gene, 54044 Neighboring gene predicted gene, 41846 Neighboring gene STARR-seq mESC enhancer starr_46135 Neighboring gene STARR-positive B cell enhancer mm9_chr19:40895901-40896202 Neighboring gene predicted gene, 33482 Neighboring gene cyclin J Neighboring gene RIKEN cDNA E030044B06 gene Neighboring gene STARR-seq mESC enhancer starr_46136 Neighboring gene predicted gene, 57494

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in non-motile cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to ciliary transition zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ciliary transition zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein CC2D2B

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001376940.1 → NP_001363869.1  protein CC2D2B

      Status: VALIDATED

      Source sequence(s)
      AC117253, AC166063, AC169520
      UniProtKB/TrEMBL
      A0A286YDU8
      Related
      ENSMUSP00000153384.2, ENSMUST00000224596.2
      Conserved Domains (3) summary
      pfam15625
      Location:465 → 632
      CC2D2AN-C2; CC2D2A N-terminal C2 domain
      pfam17661
      Location:23 → 260
      DUF5523; Family of unknown function (DUF5523)
      cl14603
      Location:907 → 940
      C2; C2 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      40737197..40818227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247419.3 → XP_011245721.2  protein CC2D2B isoform X1

      UniProtKB/TrEMBL
      A0A286YDU8
      Conserved Domains (3) summary
      pfam15625
      Location:504 → 671
      CC2D2AN-C2; CC2D2A N-terminal C2 domain
      pfam17661
      Location:23 → 260
      DUF5523; Family of unknown function (DUF5523)
      cl14603
      Location:946 → 979
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials